Recent findings suggest a pivotal role for mitochondria-associated hexokinase in the
regulation of apoptosis in animal cells. In this study, virus-induced gene silencing (VIGS) of a …

Recent findings suggest a pivotal role for mitochondria-associated hexokinase in the
regulation of apoptosis in animal cells. In this study, virus-induced gene silencing (VIGS) of a …

Previously, we reported that mitochondria-associated hexokinases are active in controlling
programmed cell death in plants (Plant Cell 18, 2341-2355). Here, we investigated their role …

''By the time I was born, more of me had died than survived. It was no wonder I cannot
remember; during that time I went through brain after brain for nine months, finally contriving …

In mammals, hexokinase (HK) is strategically located at the outer membrane of mitochondria
bound to the porin protein. The mitochondrial HK is a crucial modulator of apoptosis and …

Sequencing data from 10 species show that a plant hexokinase (HXK) family contains 5–11
genes. Functionally, a given family can include metabolic catalysts, glucose signaling …

Abstract HEXOKINASE1 (HXK1) from Arabidopsis (Arabidopsis thaliana) has dual roles in
glucose (Glc) signaling and in Glc phosphorylation. The cellular context, though, for HXK1 …

Hexokinase, a hexose-phosphorylating enzyme, has emerged as a central enzyme in sugar-
sensing processes. A few HXK isozymes have been identified in various plant species …

Alterations in glucose metabolism have been demonstrated for diverse disorders ranging
from heart disease to cancer. The first step in glucose metabolism is carried out by the …

To coordinate a meaningful response to infection or tissue damage, Tumor Necrosis Factor
(TNF) triggers a spectrum of reactions in target cells that includes cell activation …