Synthesis of high loading and encapsulation efficient paclitaxel-loaded poly (n-butyl cyanoacrylate) nanoparticles via miniemulsion

CY Huang, CM Chen, YD Lee - International journal of pharmaceutics, 2007 - Elsevier
The manufacture of stable paclitaxel-loaded poly (n-butyl cyanoacrylate)(PBCA)
nanoparticles containing high loading and encapsulation efficiency simultaneously were …

Enhancing anti-cancer efficacy of carboplatin by PEGylated poly (butyl cyanoacrylate) nano-particles

M Hassanzadeganroudsari, A Heydarinasab… - Journal of Drug Delivery …, 2019 - Elsevier
Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

Core-shell type of nanoparticles composed of poly [(n-butyl cyanoacrylate)-co-(2-octyl cyanoacrylate)] copolymers for drug delivery application: synthesis …

CY Huang, YD Lee - International journal of pharmaceutics, 2006 - Elsevier
Core-shell type of nanoparticles (NPs) with manipulated degradation rate and balanced
hydrophilic/hydrophobic properties were designed and characterized. The NPs based on …

Effect of surfactant on fabrication and characterization of paclitaxel-loaded polybutylcyanoacrylate nanoparticulate delivery systems

A Mitra, S Lin - Journal of pharmacy and pharmacology, 2003 - academic.oup.com
The feasibility of applying biodegradable polybutylcyanoacrylate (PBCA) nanoparticulate
delivery systems (NDSs) for the controlled release of paclitaxel was investigated. Paclitaxel …

[HTML][HTML] Effect of process and formulation variables on the preparation of parenteral paclitaxel-loaded biodegradable polymeric nanoparticles: A co-surfactant study

N Sharma, P Madan, S Lin - Asian journal of pharmaceutical sciences, 2016 - Elsevier
The purpose of this study was to evaluate the effect of process (homogenization speed and
evaporation time) and formulation (aqueous/organic phase ratio, surfactant concentration …

Doxorubicin‐loaded poly (butylcyanoacrylate) nanoparticles produced by emulsifier‐free emulsion polymerization

SC Yang, HX Ge, Y Hu, XQ Jiang… - Journal of applied …, 2000 - Wiley Online Library
ABSTRACT: Doxorubicin‐loaded poly (butylcyanoacrylate)(PBCA) nanoparticles (NPs)
were prepared by an emulsifier‐free emulsion polymerization technique. The pH values of …

Nanoparticles of biodegradable polymers for clinical administration of paclitaxel

SS Feng, L Mu, KY Win, G Huang - Current Medicinal Chemistry, 2004 - ingentaconnect.com
Paclitaxel is one of the best antineoplastic drugs found from nature in the past decades,
which has been found effective against a wide spectrum of cancers including ovarian …

Preparation of poly (butylcyanoacrylate) drug carriers by nanoprecipitation using a pre-synthesized polymer and different colloidal stabilizers

GG Yordanov, CD Dushkin - Colloid and Polymer Science, 2010 - Springer
Classically, drug-loaded poly (alkylcyanoacrylate) colloidal carriers are prepared by the
drug entrapment during emulsion polymerization. However, a number of chemically …

PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio

L Mu, SS Feng - Pharmaceutical research, 2003 - Springer
Purpose. We successfully manufactured nanoparticles of biodegradable polymers for
controlled release of paclitaxel. TPGS (d-α-tocopheryl polyethylene glycol 1000 succinate) …

Preparation, characterization and biocompatibility of poly (ethylene glycol)-poly (n-butyl cyanoacrylate) nanocapsules with oil core via miniemulsion polymerization

Y Zhang, S Zhu, L Yin, F Qian, C Tang, C Yin - European Polymer Journal, 2008 - Elsevier
A new type of nanocapsules with an oil core, coated by poly (ethylene glycol)(PEG) was
designed. The loading efficiency and the biocompatibility of the polymeric nanocapsules …