Ion channels as antivirus targets
X Liang, Z Li - Virologica Sinica, 2010 - Springer
Ion channels are membrane proteins that are found in a number of viruses and which are of
crucial physiological importance in the viral life cycle. They have one common feature in that …
crucial physiological importance in the viral life cycle. They have one common feature in that …
[HTML][HTML] Viral proteins function as ion channels
Viral ion channels are short membrane proteins with 50–120 amino acids and play an
important role either in regulating virus replication, such as virus entry, assembly and …
important role either in regulating virus replication, such as virus entry, assembly and …
Virus Ion Channels Formed by Vpu of HIV-1, the 6K Protein of Alphaviruses and NB of Influenza B Virus
PW Gage, G Ewart, J Melton, A Premkumar - Viral Membrane Proteins …, 2005 - Springer
One of the features of cytolytic viral infection of cells is an increase in plasma membrane
permeability. The loss of cellular metabolites and osmotic effects eventually lead to rupture …
permeability. The loss of cellular metabolites and osmotic effects eventually lead to rupture …
The ion channels coded by viruses
F Čiampor - Acta microbiologica et immunologica hungarica, 2003 - akjournals.com
Pathogenicity and virulence are multifactorial traits, depending on interaction of viruses with
susceptible cells and organisms. The ion channels coded by viruses, viroporins, represent …
susceptible cells and organisms. The ion channels coded by viruses, viroporins, represent …
[PDF][PDF] Viral ion channels as models for ion transport and targets for antiviral drug action
DLH Pinto - FEBS letters, 2004 - core.ac.uk
The recent special issue of FEBS Letters devoted to Viral Ion Channels (552/1, 18
September 2003) described a number of viral proteins that are thought to have an important …
September 2003) described a number of viral proteins that are thought to have an important …
[HTML][HTML] Viral ion channels: structure and function
WB Fischer, MSP Sansom - Biochimica et Biophysica Acta (BBA) …, 2002 - Elsevier
Viral ion channels are short auxiliary membrane proteins with a length of ca. 100 amino
acids. They are found in enveloped viruses from influenza A, influenza B and influenza C …
acids. They are found in enveloped viruses from influenza A, influenza B and influenza C …
[HTML][HTML] Unravelling the immunomodulatory effects of viral ion channels, towards the treatment of disease
S Gargan, NJ Stevenson - Viruses, 2021 - mdpi.com
The current COVID-19 pandemic has highlighted the need for the research community to
develop a better understanding of viruses, in particular their modes of infection and …
develop a better understanding of viruses, in particular their modes of infection and …
[HTML][HTML] Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles?
In 1996, three viral proteins, NB of influenza B virus prior to molecular cloning of the cDNA
and the expression of the ion channel in heterologous systems. Thus, and Vpu and Vpr of …
and the expression of the ion channel in heterologous systems. Thus, and Vpu and Vpr of …
[HTML][HTML] Ion channels as therapeutic targets for viral infections: further discoveries and future perspectives
FW Charlton, HM Pearson, S Hover, JD Lippiat… - Viruses, 2020 - mdpi.com
Ion channels play key roles in almost all facets of cellular physiology and have emerged as
key host cell factors for a multitude of viral infections. A catalogue of ion channel-blocking …
key host cell factors for a multitude of viral infections. A catalogue of ion channel-blocking …
Validation of coronavirus E proteins ion channels as targets for antiviral drugs
L Wilson, P Gage, G Ewart - The Nidoviruses: Toward Control of SARS …, 2006 - Springer
Coronaviruses are divided into three groups, depending on the sequence homology and
antigen cross-reactivity. Groups 1 and 2 contain the mammalian coronaviruses, and group 3 …
antigen cross-reactivity. Groups 1 and 2 contain the mammalian coronaviruses, and group 3 …