Widespread occurrence of phage-encoded exotoxin genes in terrestrial and aquatic environments in Southern California
V Casas, J Miyake, H Balsley, J Roark… - FEMS microbiology …, 2006 - academic.oup.com
Many human diseases are caused by pathogens that produce exotoxins. The genes that
encode these exotoxins are frequently encoded by mobile DNA elements such as plasmids …
encode these exotoxins are frequently encoded by mobile DNA elements such as plasmids …
Role of bacteriophage-encoded exotoxins in the evolution of bacterial pathogens
V Casas, S Maloy - Future microbiology, 2011 - Future Medicine
Recent advances in metagenomics research have generated a bounty of information that
provides insight into the dynamic genetic exchange occurring between bacteriophage …
provides insight into the dynamic genetic exchange occurring between bacteriophage …
[HTML][HTML] Reservoir of bacterial exotoxin genes in the environment
V Casas, J Magbanua, G Sobrepena… - International Journal of …, 2010 - hindawi.com
Many bacteria produce secreted virulence factors called exotoxins. Exotoxins are often
encoded by mobile genetic elements, including bacteriophage (phage). Phage can transfer …
encoded by mobile genetic elements, including bacteriophage (phage). Phage can transfer …
Bacteriophage-encoded shiga toxin gene in atypical bacterial host
V Casas, G Sobrepeña, B Rodriguez-Mueller, J AhTye… - Gut pathogens, 2011 - Springer
Background Contamination from fecal bacteria in recreational waters is a major health
concern since bacteria capable of causing human disease can be found in animal feces …
concern since bacteria capable of causing human disease can be found in animal feces …
Multiplex PCR for detection of the heat-labile toxin gene and shiga-like toxin I and II genes in Escherichia coli isolated from natural waters
AL Lang, YL Tsai, CL Mayer, KC Patton… - Applied and …, 1994 - Am Soc Microbiol
A triplex PCR method was developed to simultaneously amplify a heat-labile toxin sequence
(LT) of 258 bp, a shiga-like toxin I sequence (SLT I) of 130 bp, and a shiga-like toxin II …
(LT) of 258 bp, a shiga-like toxin I sequence (SLT I) of 130 bp, and a shiga-like toxin II …
Comparison of Vero-cytotoxin-encoding Phages from Escherichia coli of Human and Bovine Origin
P Rietra, GA Willshaw, HR Smith, AM Field… - …, 1989 - microbiologyresearch.org
Phages encoding production of Vero cytotoxins VT1 or VT2 were isolated from strains of
Escherichia coli of human and bovine origin. Two human strains of serotype Ol57: H7 …
Escherichia coli of human and bovine origin. Two human strains of serotype Ol57: H7 …
Diversity and host range of Shiga toxin-encoding phage
SD Gamage, AK Patton, JF Hanson… - Infection and …, 2004 - Am Soc Microbiol
ABSTRACT Shiga toxin 2 (Stx2) from the foodborne pathogen Escherichia coli O157: H7 is
encoded on a temperate bacteriophage. Toxin-encoding phages from C600:: 933W and …
encoded on a temperate bacteriophage. Toxin-encoding phages from C600:: 933W and …
Shiga toxins even when different are encoded at identical positions in the genomes of related temperate bacteriophages
H Karch, H Schmidt, C Janetzki-Mittmann… - Molecular and General …, 1999 - Springer
The nucleotide sequence of an 11,142-bp region including the stx 2 operon in the genome
of the temperate bacteriophage 933W in the EDL933 strain of Escherichia coli O157 was …
of the temperate bacteriophage 933W in the EDL933 strain of Escherichia coli O157 was …
Free Shiga toxin bacteriophages isolated from sewage showed diversity although the stx genes appeared conserved
M Muniesa, R Serra‐Moreno… - Environmental …, 2004 - Wiley Online Library
Phages carrying the stx2 gene were detected in a range of sewage samples using a plaque
hybridization‐based method. After detection, phages were isolated and propagated with a …
hybridization‐based method. After detection, phages were isolated and propagated with a …
Identification of shiga toxin-producing bacteria by a new immuno-capture toxin gene PCR
W Luo, S Wang, X Peng - FEMS microbiology letters, 2002 - academic.oup.com
Infections with bacteria producing shiga toxin are responsible for widespread disease and
for the death of a large number of people. In the present study, we have developed a rapid …
for the death of a large number of people. In the present study, we have developed a rapid …