Zebrafish models to study drug abuse-related phenotypes

A Stewart, K Wong, J Cachat, S Gaikwad, E Kyzar… - 2011 - degruyter.com
Mounting evidence implicates the zebrafish (Danio rerio) as a promising model species for
reward and addiction research. Modeling drug abuse-related behavior in both adult and …

[HTML][HTML] Understanding the neurobiological effects of drug abuse: Lessons from zebrafish models

TE Müller, BD Fontana, KT Bertoncello… - Progress in Neuro …, 2020 - Elsevier
Drug abuse and brain disorders related to drug comsumption are public health problems
with harmful individual and social consequences. The identification of therapeutic targets …

Modeling withdrawal syndrome in zebrafish

J Cachat, P Canavello, M Elegante, B Bartels… - Behavioural brain …, 2010 - Elsevier
The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral
neuroscience research. Zebrafish behavior is robustly affected by environmental and …

The zebrafish as a model system for assessing the reinforcing properties of drugs of abuse

J Ninkovic, L Bally-Cuif - Methods, 2006 - Elsevier
Recent reports make use of the zebrafish to study complex behavior such as addiction,
anxiety, or learning and memory. We have established reliable tests and appropriate …

Zebrafish: a model for the study of addiction genetics

EW Klee, H Schneider, KJ Clark, MA Cousin, JO Ebbert… - Human genetics, 2012 - Springer
Drug abuse and dependence are multifaceted disorders with complex genetic
underpinnings. Identifying specific genetic correlates is challenging and may be more …

Anxiogenic effects of cocaine withdrawal in zebrafish

MA López-Patiño, L Yu, H Cabral, IV Zhdanova - Physiology & behavior, 2008 - Elsevier
Continued usage of cocaine is determined by genetic, conditioned and homeostatic factors,
while it is reinforced by drug-induced reward and the emotionally negative state of drug …

Gender differences in zebrafish responses to cocaine withdrawal

MAL Patiño, L Yu, BK Yamamoto, IV Zhdanova - Physiology & behavior, 2008 - Elsevier
The acute responses to cocaine and its withdrawal contribute to cocaine dependence and
potentiate relapse, with gender being one of the genetic factors affecting the outcome. Here …

Drinks like a fish: zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects

R Gerlai, M Lahav, S Guo, A Rosenthal - Pharmacology biochemistry and …, 2000 - Elsevier
Zebra fish may be an ideal vertebrate model system for numerous human diseases with
which the genetics and biological mechanisms of the disease may be studied. Zebra fish …

Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes

P Mathur, S Guo - Neurobiology of disease, 2010 - Elsevier
Despite massive research efforts the exact pathogenesis and pathophysiology of addiction
and neuropsychiatric disorders such as anxiety, schizophrenia and autism remain largely …

From the cover: zebrafish larvae are insensitive to stimulation by cocaine: importance of exposure route and toxicokinetics

KT Kirla, KJ Groh, AE Steuer, M Poetzsch… - Toxicological …, 2016 - academic.oup.com
Zebrafish (Danio rerio) larvae have been suggested as vertebrate model to complement or
even replace mammals for rapidly assessing behavioral effects of psychoactive drugs. Yet …