Effects on IL-1β signaling activation induced by water and organic extracts of fine particulate matter (PM2. 5) in vitro

F Xu, X Qiu, X Hu, Y Shang, M Pardo, Y Fang… - Environmental …, 2018 - Elsevier
Abstract Fine particulate matter (PM 2.5) air pollution poses a major risk to human health
worldwide, and absorbed chemicals play a key role in determining the toxicity of PM 2.5 …

PM2. 5 collected in China causes inflammatory and oxidative stress responses in macrophages through the multiple pathways

K Bekki, T Ito, Y Yoshida, C He, K Arashidani… - Environmental …, 2016 - Elsevier
Air pollution continues to increase in East Asia, particularly in China, and is considered to
cause serious health problems. In this study, we investigated the toxicological properties of …

[HTML][HTML] Investigation of the chemical components of ambient fine particulate matter (PM2. 5) associated with in vitro cellular responses to oxidative stress and …

F Xu, X Shi, X Qiu, X Jiang, Y Fang, J Wang, D Hu… - Environment …, 2020 - Elsevier
Abstract Fine particulate matter (PM 2.5) poses a significant risk to human health worldwide,
by promoting oxidative stress and inflammation; however, the components responsible for …

PM2.5 Exposure Induces Inflammatory Response in Macrophages via the TLR4/COX-2/NF-κB Pathway

H Fu, X Liu, W Li, Y Zu, F Zhou, Q Shou, Z Ding - Inflammation, 2020 - Springer
Fine particulate matter with an aerodynamic diameter less than 2.5 μm (PM2. 5) is a serious
air pollutant associated with health problems. Macrophages play an important role in the …

Ambient particulate matter induces interleukin-8 expression through an alternative NF-κB (nuclear factor-kappa B) mechanism in human airway epithelial cells

R Silbajoris, AR Osornio-Vargas… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Exposure to ambient air particulate matter (PM) has been shown to increase
rates of cardiopulmonary morbidity and mortality, but the underlying mechanisms are still not …

TNFα and IL-6 Responses to Particulate Matter in Vitro: Variation According to PM Size, Season, and Polycyclic Aromatic Hydrocarbon and Soil Content

N Manzano-León, J Serrano-Lomelin… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: Observed seasonal differences in particulate matter (PM) associations with
human health may be due to their composition and to toxicity-related seasonal interactions …

Respiratory exposure to PM2. 5 soluble extract induced chronic lung injury by disturbing the phagocytosis function of macrophage

C Zhao, W Pu, M Niu, J Wazir, S Song, L Wei… - … Science and Pollution …, 2022 - Springer
Exposure to airborne urban particles is a contributing factor for the development of multiple
types of respiratory diseases; its pathological role as a cause of lung injury is still unclear. In …

Biological effects of airborne fine particulate matter (PM2. 5) exposure on pulmonary immune system

T Wei, M Tang - Environmental toxicology and pharmacology, 2018 - Elsevier
Airborne fine particulate matter (PM 2.5) attracts more and more attention due to its
environmental effects. The immune system appears to be a most sensitive target organ for …

Ambient fine particulate matter (PM2. 5) induces oxidative stress and pro-inflammatory response via up-regulating the expression of CYP1A1/1B1 in human bronchial …

Q Yuan, Y Chen, X Li, Z Zhang, H Chu - Mutation Research/Genetic …, 2019 - Elsevier
We investigated the mechanism responsible for the oxidative stress and pro-inflammatory
response triggered by PM 2.5 collected from Nanjing of China. Two human bronchial …

Oxidative stress and endocytosis are involved in upregulation of interleukin‐8 expression in airway cells exposed to PM 2.5

Z Yan, J Wang, J Li, N Jiang, R Zhang… - Environmental …, 2016 - Wiley Online Library
ABSTRACT Inhaled PM2. 5 (particulate matter with an aerodynamic diameter of 2.5 μm or
less) can induce lung inflammation through released inflammatory mediators from airway …