Preadmission use of renin–angiotensin blockers and rupture of abdominal aortic aneurysm: a nationwide, population‐based study

H Wemmelund, A Høgh, HH Hundborg… - … and Drug Safety, 2016 - Wiley Online Library
Purpose Rupture of abdominal aortic aneurysms (rAAA) is associated with high mortality.
Use of angiotensin converting enzyme inhibitors (ACE‐inhibitors) and angiotensin receptor …

Abdominal aortic aneurysms pharmacoepidemiological studies.

H Wemmelund - Danish Medical Journal, 2017 - europepmc.org
An abdominal aortic aneurysm (AAA) is an enlargement of the abdominal aorta. It is a
common disease in the elderly, with a prevalence of 1-5%. An AAA is normally …

Systematic Review Examining the Association of Angiotensin Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Prescription with Abdominal Aortic …

K Tian, S Thanigaimani, K Gibson… - European Journal of …, 2024 - Elsevier
Objective Whether angiotensin II blockade is an effective medical treatment for abdominal
aortic aneurysms (AAAs) has not been established. This systematic review and meta …

Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in patients with abdominal aortic aneurysms: nation-wide cohort study

KE Kristensen, C Torp-Pedersen… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—The renin–angiotensin system is thought to play a pivotal role in the
pathogenesis of abdominal aortic aneurysms (AAAs). However, effects of angiotensin …

Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study

DG Hackam, D Thiruchelvam, DA Redelmeier - The Lancet, 2006 - thelancet.com
Background Angiotensin-converting enzyme (ACE) inhibitors prevent the expansion and
rupture of aortic aneurysms in animals. We investigated the association between ACE …

[HTML][HTML] Renin-angiotensin system blockade does not attenuate abdominal aortic aneurysm growth, rupture rate, or perioperative mortality after elective repair

K Salata, M Syed, MA Hussain, R Eikelboom… - Journal of vascular …, 2018 - Elsevier
Objective The objective of this study was to summarize the literature regarding the effects of
renin-angiotensin system blockade (RASB) using angiotensin-converting enzyme inhibitors …

[HTML][HTML] Low-dose aspirin and rupture of abdominal aortic aneurysm

H Wemmelund, TMM Jørgensen, A Høgh… - Journal of Vascular …, 2017 - Elsevier
Objective The use of low-dose aspirin (acetylsalicylic acid [ASA]) has been suggested to
attenuate growth of abdominal aortic aneurysms (AAAs), yet solid clinical evidence of this …

Renin‐Angiotensin‐Aldosterone System Inhibitors Are Associated With Favorable Outcomes Compared to Beta Blockers in Reducing Mortality Following Abdominal …

N Elsayed, AC Gaffey, A Abou‐Zamzam… - Journal of the …, 2023 - Am Heart Assoc
Background The best medical therapy to control hypertension following abdominal aortic
aneurysm repair is yet to be determined. We therefore examined whether treatment with …

A retrospective study: factors associated with the risk of abdominal aortic aneurysm rupture

VJ Gokani, D Sidloff, MF Bath, MJ Bown… - Vascular …, 2015 - Elsevier
Introduction Literature regarding pharmacological manipulation of aneurysm development
and progression is abundant; however studies looking at preventing rupture are sparse …

Statin use and rupture of abdominal aortic aneurysm

H Wemmelund, A Høgh, HH Hundborg… - Journal of British …, 2014 - academic.oup.com
Background Ruptured abdominal aortic aneurysm (rAAA) is associated with high mortality.
Research suggests that statins may reduce abdominal aortic aneurysm (AAA) growth and …