Synucleinopathies are diverse diseases with motor and cognitive dysfunction due to
progressive neuronal loss or demyelination, due to oligodendrocyte loss in the brain. While …

The accumulation of α-synuclein (αSyn) has been implicated as a causal factor in the
pathogenesis of Parkinson's disease (PD). There is growing evidence that supports …

α-Synuclein is an abundant neuronal protein that accumulates in insoluble inclusions in
Parkinson′ s disease and other synucleinopathies. Fatty acids partially regulate α …

Neuronal loss in Parkinson's disease and related brain diseases has been firmly linked to
the abundant neuronal protein α-synuclein (αS). However, we have gained surprisingly little …

An aging society leads to an increased number of patients with cognitive and movement
disorders, such as Parkinson's disease and dementia with Lewy bodies. α-Synuclein …

Parkinson's disease (PD) and multiple system atrophy are types of adult-onset
neurodegenerative disorders named synucleinopathies, which are characterized by …

The abnormal accumulation of alpha-synuclein (α-syn) aggregates in neurons and glial cells
is widely known to be associated with many neurodegenerative diseases, including …

Oligomerization and/or aggregation of α-synuclein (α-Syn) triggers α-synucleinopathies
such as Parkinson's disease and dementia with Lewy bodies. It is known that α-Syn can …

Alpha-synuclein aggregation and mitochondrial dysfunction are main pathological hallmarks
of Parkinson's disease (PD) and several other neurodegenerative diseases, collectively …

α-Synuclein (αSyn) accumulation in dopaminergic (DA) neurons is partly regulated by long-
chain polyunsaturated fatty acids. We found that fatty acid-binding protein 3 (FABP3, H …