Osteoporosis (OP) is a systemic bone disease characterized by decreased bone strength,
microarchitectural changes in bone tissues, and increased risk of fracture. Its occurrence is …

Bone is a dynamic tissue composed of cells, an extracellular matrix, and mineralized portion.
Osteoblasts are responsible for proper bone formation and remodeling, and function. These …

Many epidemiological studies show a positive connection between cardiovascular diseases
and risk of osteoporosis, suggesting a role of hyperlipidemia and/or hypercholesterolemia in …

Oxysterols play a critical role in human health and diseases associated with high cholesterol
and oxidative stress. Given that a positive correlation was observed between cholesterol …

As the incidence of osteoporosis (OP) and hypercholesterolaemia in men has increased,
male OP has drawn more attention from clinicians worldwide. The present study sought to …

Cellular aging is associated with dysfunction of numerous tissues affecting multiple organ
systems. A striking example of this is related to age-related bone loss, or osteoporosis …

Bone is a complex tissue composing of mineralized bone, bone cells, hematopoietic cells,
marrow adipocytes, and supportive stromal cells. The homeostasis of bone and marrow …

Osteoporosis, characterized by bone mass reduction and increased fractures, has become a
global health problem that seriously affects the health of people, especially postmenopausal …

The association between lipid and bone metabolism has become an increasing focus of
interest in recent years, and accumulating evidence has shown that atherosclerosis (AS) …

Loss of bone mass with advancing age in mice is because of decreased osteoblast number
and is associated with increased oxidative stress and decreased canonical Wnt signaling …