NUT carcinoma
CA French - Rare Tumors in Children and Adolescents, 2022 - Springer
NUT carcinoma (NC) is defined molecularly by rearrangement of the NUTM1 gene and is
most commonly driven by the BRD4-NUT oncoprotein. Patients are typically in their teens or …
most commonly driven by the BRD4-NUT oncoprotein. Patients are typically in their teens or …
NUT Carcinoma: Clinicopathologic features, pathogenesis, and treatment
CA French - Pathology international, 2018 - Wiley Online Library
NUT carcinoma (NC) is a rare, aggressive subtype of squamous cell carcinoma defined by
rearrangement of the NUTM1 (aka NUT) gene. NC is driven by NUT‐fusion oncoproteins …
rearrangement of the NUTM1 (aka NUT) gene. NC is driven by NUT‐fusion oncoproteins …
[HTML][HTML] NUT carcinoma—an underdiagnosed malignancy
UM Lauer, M Hinterleitner, M Horger… - Frontiers in …, 2022 - frontiersin.org
NUT carcinoma (NC) is a rare and highly aggressive malignancy with a dismal prognosis
and a median survival of 6–9 months only. Although very few cases of NC are reported each …
and a median survival of 6–9 months only. Although very few cases of NC are reported each …
Diagnosis of NUT carcinoma of lung origin by next-generation sequencing: case report and review of the literature
N Mao, Z Liao, J Wu, K Liang, S Wang… - Cancer Biology & …, 2019 - Taylor & Francis
ABSTRACT NUT carcinoma (NC) is an aggressive squamous tumor characterized by NUT
gene rearrangement, and the most common fusion form is BRD4-NUT. However, NC …
gene rearrangement, and the most common fusion form is BRD4-NUT. However, NC …
Report of the first international symposium on NUT carcinoma
NUT carcinoma is a rare, aggressive cancer defined by rearrangements of the NUTM1 gene.
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …
NUT carcinoma
LR Chirieac, CA French - … lesions: diagnostic pearls for interpretation of …, 2017 - Springer
NUT carcinoma (NC) is a genetically defined, highly aggressive, and incurable squamous
cell carcinoma associated with chromosomal rearrangements of NUT, most commonly …
cell carcinoma associated with chromosomal rearrangements of NUT, most commonly …
A case of metastatic NUT carcinoma with prolonged response on gemcitabine and nab‐paclitaxel
SA Patel, B Singer, C Shen, AM Zanation… - Clinical Case …, 2021 - Wiley Online Library
Background NUT carcinoma is an aggressive malignancy characterized by translocations in
the NUTM1 gene. There are currently no consensus treatment recommendations for NUT …
the NUTM1 gene. There are currently no consensus treatment recommendations for NUT …
[HTML][HTML] NUTM1-rearranged neoplasia: a multi-institution experience yields novel fusion partners and expands the histologic spectrum
TM Stevens, D Morlote, J Xiu, J Swensen… - Modern Pathology, 2019 - Elsevier
Poorly differentiated neoplasms lacking characteristic histopathologic features represent a
significant challenge to the pathologist for diagnostic classification. Classically, NUT …
significant challenge to the pathologist for diagnostic classification. Classically, NUT …
Salivary gland NUT carcinoma with prolonged survival in children: case illustration and systematic review of literature
H Wang, VL Weiss, RD Hoffman, T Abel, RH Ho… - Head and neck …, 2021 - Springer
NUT (midline) carcinoma is a rare, highly aggressive, poorly differentiated carcinoma that
characteristically harbors a rearrangement of the NUTM1 gene. Most of these tumors occur …
characteristically harbors a rearrangement of the NUTM1 gene. Most of these tumors occur …
[HTML][HTML] Clinical management of NUT carcinoma (NC) in Germany: Analysis of survival, therapy response, tumor markers and tumor genome sequencing in 35 adult …
LD Kloker, M Sidiras, T Flaadt, IB Brecht, CKW Deinzer… - Lung Cancer, 2024 - Elsevier
NUT carcinomas (NC) are very rare and highly aggressive tumors, molecularly defined by
an aberrant gene fusion involving the NUTM1 gene. NCs preferentially arise …
an aberrant gene fusion involving the NUTM1 gene. NCs preferentially arise …