No significant association between genetic variants in 7 candidate genes and response to methylphenidate treatment in adult patients with ADHD

V Contini, MM Victor, GP Bertuzzi… - Journal of clinical …, 2012 - journals.lww.com
Results from pharmacogenetic investigations of methylphenidate (MPH) response in
patients with ADHD are still inconsistent, especially among adults. This study investigates …

[HTML][HTML] A candidate gene investigation of methylphenidate response in adult attention-deficit/hyperactivity disorder patients: results from a naturalistic study

TA Hegvik, KK Jacobsen, M Fredriksen… - Journal of Neural …, 2016 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood onset
neuropsychiatric disorder with a complex and heterogeneous symptomatology. Persistence …

The impact of individual and methodological factors in the variability of response to methylphenidate in ADHD pharmacogenetic studies from four different continents

G Polanczyk, SV Faraone, CHD Bau… - American Journal of …, 2008 - Wiley Online Library
Several studies have evaluated the association between individual polymorphisms and
response to methylphenidate (MPH) in subjects with attention‐deficit/hyperactivity disorder …

Response to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1)

JS Kooij, AM Boonstra, SH Vermeulen… - American Journal of …, 2008 - Wiley Online Library
In this pharmacogenetic study in adults with ADHD (n= 42), a stratified analysis was
performed of the association between response to methylphenidate (MPH), assessed under …

Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD

H Tharoor, EA Lobos, RD Todd… - American Journal of …, 2008 - Wiley Online Library
Gene polymorphisms of the 3′ untranslated region (3′‐UTR) of the dopamine transporter
(DAT1), Dopamine receptor exon 3 D4 variable number tandem repeat (DRD4VNTR) …

Pharmacogenetics of response to methylphenidate in adult patients with attention-deficit/hyperactivity disorder (ADHD): a systematic review

V Contini, DL Rovaris, MM Victor, EH Grevet… - European …, 2013 - Elsevier
Methylphenidate (MPH) is a first line option in the psychopharmacologic treatment of adults
with Attention-Deficit/Hyperactivity Disorder (ADHD). However, there is a considerable …

A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder

JJ McGough, JT McCracken, SK Loo… - Journal of the American …, 2009 - Elsevier
OBJECTIVE: This study examines the potential role of candidate genes in moderating
treatment effects of methylphenidate (MPH) in attention-deficit/hyperactivity disorder …

Pharmacogenetics of methylphenidate response and tolerability in attention-deficit/hyperactivity disorder

M Pagerols, V Richarte, C Sánchez-Mora… - The …, 2017 - nature.com
Methylphenidate (MPH) is the most frequently used pharmacological treatment in children
with attention-deficit/hyperactivity disorder. However, a considerable interindividual …

Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder

TE Froehlich, JN Epstein, TG Nick, MSM Castro… - Journal of the American …, 2011 - Elsevier
OBJECTIVE: Because of significant individual variability in attention-deficit/hyperactivity
disorder (ADHD) medication response, there is increasing interest in identifying genetic …

Pharmacogenetics of methylphenidate response in preschoolers with ADHD

J McGOUGH, J McCRACKEN, J Swanson… - Journal of the American …, 2006 - Elsevier
OBJECTIVE: The authors explored genetic moderators of symptom reduction and side
effects in methylphenidate-treated preschool-age children diagnosed with attention …