We have isolated subsets of cells from human PBL and have investigated their abilities to
mediate lysis targeted by bispecific antibodies. Targeted cytotoxic cells were divided into two …

A leukocyte population consisting of approximately 85% lymphocytes, prepared from human
peripheral blood by centrifugation through a Ficoll-Hypaque gradient, was studied for its …

We have induced fresh peripheral blood K/natural killer cells to lyse a variety of target cells
by coating them with anti-Fc gamma receptor (anti-Fc gamma R)(CD16) antibody hetero …

Nonadherent and nonphagocytic lymphoid cells from human peripheral blood became
strongly cytotoxic against 51Cr‐labeled chicken red blood cells and cells from an …

Cytotoxic T lymphocytes were found to mediate rapid lysis of target cells not normally
recognized in the presence of small polystyrene beads coated with a combination of anti-T3 …

We have compared the mechanisms by which human PBL targeted with bispecific
antibodies either lyse tumor cells or block their growth in culture or in mice. We found that …

We have studied the ability of purified B lymphocytes to generate cytotoxic T lymphocytes in
autologous mixed leukocyte cultures (MLC). Cytotoxic lymphocytes were produced but only …

The specificity and efficiency of tumor‐cell lysis by the retargeting of murine cytolytic
lymphocytes (CTL) with bispecific antibodies was examined. Bispecific antibodies (also …

DNP-specific, class II-restricted cloned T cells were shown to kill DNP-bearing A20. 2J (A20-
DNP) antigen-presenting cells. This killing was DNP-specific and was restricted by IA …

Cytotoxic T lymphocytes (CL) can be produced by culturing I region disparate spleen cells
as previously reported. More recently, it was shown that these CL can lyse other target cells …