Protection of glycyrrhizic acid against AGEs-induced endothelial dysfunction through inhibiting RAGE/NF-κB pathway activation in human umbilical vein endothelial …

L Feng, M Zhu, M Zhang, R Wang, X Tan, J Song… - Journal of …, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Licorice (Glycyrrhiza uralensis roots) is used
as a traditional medicine for the treatment of diabetes mellitus and its vascular …

The protective effect of Smilax glabra extract on advanced glycation end products-induced endothelial dysfunction in HUVECs via RAGE-ERK1/2-NF-κB pathway

H Sang, J Gu, J Yuan, M Zhang, X Jia, L Feng - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Smilax glabra Roxb.(SGR) is a traditional
Chinese herb that has been used in folk for the treatment of diabetic vascular complications …

Liquiritin attenuates advanced glycation end products-induced endothelial dysfunction via RAGE/NF-κB pathway in human umbilical vein endothelial cells

X Zhang, Y Song, X Han, L Feng, R Wang… - Molecular and cellular …, 2013 - Springer
Advanced glycation end products (AGEs)-induced vasculopathy, including oxidative stress,
inflammation and apoptosis responses, contributes to the high morbidity and mortality of …

[HTML][HTML] Glycine suppresses AGE/RAGE signaling pathway and subsequent oxidative stress by restoring Glo1 function in the aorta of diabetic rats and in HUVECs

Z Wang, J Zhang, L Chen, J Li, H Zhang… - Oxidative Medicine and …, 2019 - hindawi.com
Oxidative stress plays a crucial role in the pathogenesis of diabetic vascular complications. It
is known that the accumulation of advanced glycation end products (AGEs) and the …

Apigenin and its methylglyoxal-adduct inhibit advanced glycation end products-induced oxidative stress and inflammation in endothelial cells

Q Zhou, KW Cheng, J Gong, ETS Li, M Wang - Biochemical Pharmacology, 2019 - Elsevier
Protein glycation in the body can lead to malfunction of intracellular and extracellular
proteins. Reactive carbonyl species (RCS) have been identified to be key intermediates in …

[HTML][HTML] Dietary flavonoids alleviate inflammation and vascular endothelial barrier dysfunction induced by advanced glycation end products in vitro

Y Fu, Y Jia, Y Sun, X Liu, J Yi, S Cai - Nutrients, 2022 - mdpi.com
The aim of this study was to compare the protective effects of three dietary flavonoids
(apigenin-7-O-glucoside (A7G), isorhamnetin-3-O-rutinoside (I3R), and cyanidin-3-O …

Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs

R Hu, M Wang, S Ni, M Wang, L Liu, H You… - European Journal of …, 2020 - Elsevier
Endothelial dysfunction plays important roles in vascular dysfunction under diabetic
conditions. The generation of advanced glycation end products (AGEs), which can induce …

[HTML][HTML] N-butanol extracts of Morinda citrifolia suppress advanced glycation end products (AGE)-induced inflammatory reactions in endothelial cells through its anti …

Y Ishibashi, T Matsui, F Isami, Y Abe… - … and alternative medicine, 2017 - Springer
Background Advanced glycation end products (AGEs), senescent macroprotein derivatives
formed during a normal aging process and acceleratedly under diabetic conditions, play a …

Inhibitory effect of GSPE on RAGE expression induced by advanced glycation end products in endothelial cells

FL Zhang, HQ Gao, L Shen - Journal of cardiovascular …, 2007 - journals.lww.com
Advanced glycation end products'(AGEs) engagement of a cell-surface receptor for AGEs
(RAGE) has been causally implicated in the pathogenesis of diabetic vascular complications …

RETRACTED ARTICLE: Attenuation of aortic injury by ursolic acid through RAGE-Nox-NFκB pathway in streptozocin-induced diabetic rats

M Xiang, J Wang, Y Zhang, J Ling, X Xu - Archives of pharmacal research, 2012 - Springer
Vascular complications are the leading causes of morbidity and mortality in diabetes mellitus
(DM). The RAGE (receptor for advanced glycation end products)-NADPH oxidase-NF-κB …