Molecular evolution of the GATA family of transcription factors: conservation within the DNA-binding domain

JA Lowry, WR Atchley - Journal of molecular evolution, 2000 - Springer
The GATA-binding transcription factors comprise a protein family whose members contain
either one or two highly conserved zinc finger DNA-binding domains. Members of this group …

Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA

DL Bates, Y Chen, G Kim, L Guo, L Chen - Journal of molecular biology, 2008 - Elsevier
The GATA family of transcription factors (GATA1–6) binds selected GATA sites in vertebrate
genomes to regulate specific gene expression. Although vertebrate GATA factors have two …

DNA-binding specificity of GATA family transcription factors

M Merika, SH Orkin - Molecular and cellular biology, 1993 - Taylor & Francis
GATA-binding proteins constitute a family of transcription factors that recognize a target site
conforming to the consensus WGATAR (W= A or T and R= A or G). Here we have used the …

[HTML][HTML] GATA zinc finger interactions modulate DNA binding and transactivation

CD Trainor, R Ghirlando, MA Simpson - Journal of Biological Chemistry, 2000 - ASBMB
GATA-1 and other vertebrate GATA factors contain a DNA binding domain composed of two
adjacent homologous zinc fingers. Whereas only the C-terminal finger of GATA-1 is capable …

The GATA family of transcription factors in Arabidopsis and rice

JC Reyes, MI Muro-Pastor, FJ Florencio - Plant physiology, 2004 - academic.oup.com
GATA transcription factors are a group of DNA binding proteins broadly distributed in
eukaryotes. The GATA factors DNA binding domain is a class IV zinc finger motif in the form …

Plant GATA factors: their biology, phylogeny, and phylogenomics

C Schwechheimer, PM Schröder… - Annual review of plant …, 2022 - annualreviews.org
GATA factors are evolutionarily conserved transcription factors that are found in animals,
fungi, and plants. Compared to that of animals, the size of the plant GATA family is …

[PDF][PDF] DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation

Y Chen, DL Bates, R Dey, PH Chen, ACD Machado… - Cell reports, 2012 - cell.com
GATA transcription factors regulate transcription during development and differentiation by
recognizing distinct GATA sites with a tandem of two conserved zinc fingers, and by …

[HTML][HTML] B-GATA transcription factors–insights into their structure, regulation, and role in plant development

C Behringer, C Schwechheimer - Frontiers in plant science, 2015 - frontiersin.org
GATA transcription factors are evolutionarily conserved transcriptional regulators that
recognize promoter elements with a GATA core sequence. In comparison to animal …

[HTML][HTML] Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus

ML Martowicz, JA Grass, ME Boyer, H Guend… - Journal of Biological …, 2005 - ASBMB
Given the simplicity of the DNA sequence that mediates binding of GATA transcription
factors, GATA motifs reside throughout chromosomal DNA. However, chromatin …

[HTML][HTML] The N‐terminal fingers of chicken GATA‐2 and GATA–3 are independent sequence‐specific DNA binding domains

PV Pedone, JG Omichinski, P Nony, C Trainor… - The EMBO …, 1997 - embopress.org
The GATA family of vertebrate DNA binding regulatory proteins are expressed in diverse
tissues and at different times of development. However, the DNA binding regions of these …