Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes …

H Al-Kateb, AP Boright, L Mirea, X Xie, R Sutradhar… - Diabetes, 2008 - Am Diabetes Assoc
BACKGROUND—Despite familial clustering of nephropathy and retinopathy severity in type
1 diabetes, few gene variants have been consistently associated with these outcomes …

Allelic variations in superoxide dismutase-1 (SOD1) gene are associated with increased risk of diabetic nephropathy in type 1 diabetic subjects

K Mohammedi, S Maimaitiming, N Emery… - Molecular genetics and …, 2011 - Elsevier
BACKGROUND: Oxidative stress is involved in the pathophysiology of diabetic nephropathy.
The superoxide dismutase (SOD) enzymes play a major role in detoxification of reactive …

Allelic variations in superoxide dismutase-1 (SOD1) gene and renal and cardiovascular morbidity and mortality in type 2 diabetic subjects

AL Neves, K Mohammedi, N Emery, R Roussel… - Molecular genetics and …, 2012 - Elsevier
BACKGROUND: Oxidative stress is involved in the pathophysiology of renal and
cardiovascular complications of diabetes. Superoxide dismutase (SOD) enzymes play a …

The V16A polymorphism in SOD2 is associated with increased risk of diabetic nephropathy and cardiovascular disease in type 1 diabetes

A Möllsten, A Jorsal, M Lajer, N Vionnet, L Tarnow - Diabetologia, 2009 - Springer
Aims/hypothesis Hyperglycaemia increases oxidative stress and may thereby increase the
risk of diabetic complications, including diabetic nephropathy. Cells are protected from …

Manganese Superoxide Dismutase (SOD2) Polymorphisms, Plasma Advanced Oxidation Protein Products (AOPP) Concentration and Risk of Kidney Complications …

K Mohammedi, N Bellili-Munoz, F Driss, R Roussel… - PloS one, 2014 - journals.plos.org
Aims Oxidative stress is involved in the pathophysiology of diabetic nephropathy.
Manganese superoxide dismutase (SOD2) catalyses the dismutation of superoxide …

Polymorphic differences in the SOD-2 gene may affect the pathogenesis of nephropathy in patients with diabetes and diabetic complications

A Houldsworth, A Hodgkinson, S Shaw, A Millward… - Gene, 2015 - Elsevier
The effective treatment of diabetes and the prevention of diabetic complications may be
improved by a better understanding of the antioxidant function of intracellular defences …

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes

MG Pezzolesi, GD Poznik, JC Mychaleckyj… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Despite extensive evidence for genetic susceptibility to diabetic nephropathy,
the identification of susceptibility genes and their variants has had limited success. To …

Association of the C47T polymorphism in SOD2 with diabetes mellitus and diabetic microvascular complications: a meta-analysis

C Tian, S Fang, X Du, C Jia - Diabetologia, 2011 - Springer
Aims/hypothesis A meta-analysis was performed to assess the association of C47T
(rs4880)(also called Val16Ala) polymorphism in SOD2 gene with reduced risk of diabetes …

[PDF][PDF] Association of+ 35A/C (intron3/exon3) polymorphism in SOD1-gene with diabetic nephropathy in type 1 diabetes

NM Panduru, D Cimponeriu, M Cruce… - Rom J Morphol …, 2010 - researchgate.net
Diabetic nephropathy is a major complication of type 1 diabetes whose pathogenesis is
insufficiently known, but oxidative stress and genetic susceptibility seem to be involved. The …

Plasma extracellular superoxide dismutase concentration, allelic variations in the SOD3 gene and risk of myocardial infarction and all-cause mortality in people with …

K Mohammedi, N Bellili-Muñoz, SL Marklund… - Cardiovascular …, 2015 - Springer
Background Oxidative stress is involved in development of diabetes complications.
Extracellular superoxide dismutase (EC-SOD, SOD3) is a major extracellular antioxidant …