Left ventricular (LV) dysfunction and/or heart failure (HF) are frequent complications of
hypertension and myocardial infarction (MI), placing affected patients at increased risk of …

The physiological role of the renin angiotensin aldosterone system (RAAS) is to maintain the
integrity of the cardiovascular system. The effect of angiotensin II is mediated via the …

Survivors of myocardial infarction (MI) are at high risk of disability and death. This is due to
infarct-related complications such as heart failure, cardiac remodeling with progressive …

Background Actions of angiotensin II may contribute to the progression of heart failure
despite treatment with currently recommended drugs. We therefore evaluated the long-term …

Angiotensin II receptor blockers (ARBs) directly inhibit the angiotensin II type 1 receptors,
which suppresses the renin-angiotensin-aldosterone system (RAAS). Six ARBs are …

One of the important problems of the patients undergoing acute myocardial infarction (MI) is
early development of heart failure. It has been revealed in various studies that renin …

Angiotensin II receptor blockers (ARBs) are the most recent class of anti‐hypertensive drug
to enter clinical use for chronic heart failure (CHF). In the landmark Valsartan Heart Failure …

Abstract Abstract Valsartan (Diovan®) is an oral angiotensin II-receptor antagonist with
specificity for the angiotensin II type 1 receptor subtype. It demonstrates antihypertensive …

Heart failure (HF) still has a discouraging prognosis. Therapeutic strategies aim to reduce
mortality as well as slow the progression of the disease, improve symptoms and reduce the …

Angiotensin-converting enzyme inhibitors (ACE-inhibitors) are first-line treatment for chronic
heart failure (CHF) with a low left ventricular ejection fraction because they improve …