Oxidation–reduction states of NADH in vivo: from animals to clinical use
A Mayevsky, B Chance - Mitochondrion, 2007 - Elsevier
Mitochondrial dysfunction is part of many pathological states in patients, such as sepsis or
stroke. Presently, the monitoring of mitochondrial function in patients is extremely rare, even …
stroke. Presently, the monitoring of mitochondrial function in patients is extremely rare, even …
Mitochondrial function in vivo evaluated by NADH fluorescence: from animal models to human studies
A Mayevsky, GG Rogatsky - American journal of physiology …, 2007 - journals.physiology.org
Normal mitochondrial function is a critical factor in maintaining cellular homeostasis in
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …
Use of NADH fluorescence to determine mitochondrial function in vivo
A Mayevsky, E Barbiro-Michaely - … journal of biochemistry & cell biology, 2009 - Elsevier
Normal mitochondrial function is a critical factor in maintaining cellular homeostasis in
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …
Measurement of mitochondrial NADH and FAD autofluorescence in live cells
F Bartolomé, AY Abramov - Mitochondrial Medicine: Volume I, Probing …, 2015 - Springer
In the process of energy production, mitochondrial networks are key elements to allow
metabolism of substrates into ATP. Many pathological conditions have been associated with …
metabolism of substrates into ATP. Many pathological conditions have been associated with …
Mitochondrial NADH redox state, monitoring discovery and deployment in tissue
B Chance - Methods in enzymology, 2004 - Elsevier
Publisher Summary This chapter describes the origins of the study of nicotinamide adenine
dinucleotide (NADH) and fluoroprotein to show how they provide a window into the cell …
dinucleotide (NADH) and fluoroprotein to show how they provide a window into the cell …
A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression
J SeungáKim - Chemical communications, 2019 - pubs.rsc.org
Herein, we report a rhodamine-based redox probe (MQR) to visualize cytosolic NADH in the
cellular milieu. Its high sensitivity and selectivity allowed it to track the alteration of the NADH …
cellular milieu. Its high sensitivity and selectivity allowed it to track the alteration of the NADH …
In vivo NADH fluorescence
C Ince, J Coremans, HA Bruining - Oxygen transport to tissue XIV, 1992 - Springer
Reduced nicotinamide adenine dinucleotide (NADH) offers one of the main means to
transfer energy from the tricarboxylic acid cycle to the respiratory chain in the mitochondria …
transfer energy from the tricarboxylic acid cycle to the respiratory chain in the mitochondria …
Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis
Active changes in mitochondrial structure and organization facilitate cellular homeostasis.
Because aberrant mitochondrial dynamics are implicated in a variety of human diseases …
Because aberrant mitochondrial dynamics are implicated in a variety of human diseases …
Mitochondrial redox imaging for cancer diagnostic and therapeutic studies
Mitochondrial redox states provide important information about energy-linked biological
processes and signaling events in tissues for various disease phenotypes including cancer …
processes and signaling events in tissues for various disease phenotypes including cancer …
Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress
Ventilation with enhanced fractions of O 2 (hyperoxia) is a common and necessary treatment
for hypoxemia in patients with lung failure, but prolonged exposure to hyperoxia causes lung …
for hypoxemia in patients with lung failure, but prolonged exposure to hyperoxia causes lung …