Cellular and molecular correlates of ectopic activity in patients with atrial fibrillation
Atrial fibrillation (AF) is the most frequent arrhythmia and is associated with increased
morbidity and mortality. Current drugs for AF treatment have limited efficacy and a …
morbidity and mortality. Current drugs for AF treatment have limited efficacy and a …
Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and its prevalence is
increasing with the ageing of the population. Presently available treatment options are far …
increasing with the ageing of the population. Presently available treatment options are far …
Dynamic remodeling of intracellular Ca2+ signaling during atrial fibrillation
M Greiser, U Schotten - Journal of molecular and cellular cardiology, 2013 - Elsevier
During atrial fibrillation (AF) intracellular Ca2+ signaling in atrial myocytes changes
substantially. This 'remodeled'intracellular Ca2+ homeostasis plays an important role in the …
substantially. This 'remodeled'intracellular Ca2+ homeostasis plays an important role in the …
Deciphering the fundamental mechanisms of atrial fibrillation: a quest for over a century
Atrial fibrillation (AF), the most frequent clinical arrhythmia, is associated with increased
cardiovascular morbidity and mortality, with stroke, myocardial infarction, and heart failure …
cardiovascular morbidity and mortality, with stroke, myocardial infarction, and heart failure …
Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics
Atrial electrical and structural alterations (remodeling) have emerged as key elements in the
development of the atrial fibrillation (AF) substrate. Evidence points to abnormalities in …
development of the atrial fibrillation (AF) substrate. Evidence points to abnormalities in …
Alterations of atrial Ca2+ handling as cause and consequence of atrial fibrillation
M Greiser, WJ Lederer, U Schotten - Cardiovascular research, 2011 - academic.oup.com
Atrial fibrillation (AF) is the most prevalent sustained arrhythmia. As the most important risk
factor for embolic stroke, AF is associated with a high morbidity and mortality. Despite …
factor for embolic stroke, AF is associated with a high morbidity and mortality. Despite …
New insights into the molecular basis of atrial fibrillation: mechanistic and therapeutic implications
Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with substantial
cardiovascular morbidity and mortality, with stroke being the most critical complication. 1 …
cardiovascular morbidity and mortality, with stroke being the most critical complication. 1 …
[HTML][HTML] Proarrhythmic Remodeling of Atrial Myocyte Ca2+ Handling in Atrial Fibrillation
SR Houser - Basic to Translational Science, 2023 - jacc.org
Atrial fibrillation (AF) is the most common arrhythmia in the United States and other Western
nations. It is increasing in prevalence in our aging society and represents a major health …
nations. It is increasing in prevalence in our aging society and represents a major health …
The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
Atrial fibrillation (AF) is an extremely common clinical problem associated with increased
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …