Early detection of viral pathogens by DNA-sensors in clinical samples, contaminated foods,
soil or water can dramatically improve clinical outcomes and reduce the socioeconomic …

Abstract Recently Jennifer Doudna's group discovered the Clustered Regularly Interspaced
Short Palindromic Repeats (CRISPR)-CRISPR associated protein 14 (Cas14), identified …

Virus disease spreads effortlessly mechanically or through minute insect vectors that are
extremely challenging to avoid. Emergence and reemergence of new viruses such as …

The pandemic due to the outbreak of 2019 coronavirus disease (COVID-19) caused by
novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has raised significant …

Viral infections are one of the most intimidating threats to human beings. One convincing
example is the coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2. Rapid …

CRISPR-associated (Cas) protein systems have been increasingly incorporated in nucleic-
acid diagnosis. CRISPR/Cas12a can cleave single-stranded DNA (ssDNA) after being …

CRISPR/Cas system, originally developed as genetic editing tool, also shows great
potentials for nucleotide detection. A recent study published in Molecular Cell (Freije et al …

Beyond their widespread application as genome‐editing and regulatory tools, clustered
regularly interspaced short palindromic repeats (CRISPR)‐CRISPR‐associated (Cas) …

Nucleic acid detection is a necessary part of medical treatment and fieldwork. However, the
current detection technologies are far from ideal. A lack of timely and accessible testing for …

Abstract CRISPR-Cas12a (Cpf1) trans-cleaves ssDNA and this feature has been widely
harnessed for nucleic acid detection. Herein, we introduce a new type of Cas12a reporter, G …