Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31–35

D Owerbach, FJ Naya, MJ Tsai, SV Allander… - Diabetes, 1997 - Am Diabetes Assoc
Recent genome searches suggest a putative linkage of many loci to susceptibility to type I
diabetes. The chromosome 2q31–35 region is reported to be linked to susceptibility to type I …

The HOXD8 locus (2q31) is linked to type I diabetes: interaction with chromosome 6 and 11 disease susceptibility genes

D Owerbach, KH Gabbay - Diabetes, 1995 - Am Diabetes Assoc
Type I diabetes susceptibility genes have been identified within the major histocompatibility
complex (MHC) on chromosome 6p21. 3 and near the VNTR/insulin region on chromosome …

The search for type 2 diabetes susceptibility loci: the chromosome 1q story

SK Das, SC Elbein - Current diabetes reports, 2007 - Springer
The unbiased approach of genome-wide linkage analysis has shown evidence for linkage of
type 2 diabetes mellitus to the chromosome 1q21–25 region in at least eight independent …

The type 1 diabetes genetics consortium

SS Rich, P Concannon, H Erlich… - Annals of the New …, 2006 - Wiley Online Library
The Type 1 Diabetes Genetics Consortium (T1DGC) is an international, multicenter program
organized to promote research to identify genes and their alleles that determine an …

Linkage and association with type 1 diabetes on chromosome 1q42

KG Ewens, LN Johnson, B Wapelhorst, K O'Brien… - Diabetes, 2002 - Am Diabetes Assoc
Type 1 diabetes is a complex disorder with multiple genetic loci and environmental factors
contributing to disease etiology. In the current study, a human type 1 diabetes candidate …

Type 2 diabetes susceptibility genes on chromosome 1q21–24

SJ Hasstedt, WS Chu, SK Das, H Wang… - Annals of human …, 2008 - Wiley Online Library
Summary Type 2 diabetes (T2D) has been linked to chromosome 1q21–24 in multiple
samples, including a Utah family sample. Variants in 13 of the numerous candidate genes in …

[PDF][PDF] Genomewide search for type 2 diabetes susceptibility genes in four American populations

MG Ehm, MC Karnoub, H Sakul, K Gottschalk… - The American Journal of …, 2000 - cell.com
Type 2 diabetes is a serious, genetically influenced disease for which no fully effective
treatments are available. Identification of biochemical or regulatory pathways involved in the …

Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibility locus on human chromosome 8p23. 1

MG Pezzolesi, M Nam, T Nagase, T Klupa, JS Dunn… - Diabetes, 2004 - Am Diabetes Assoc
In a panel of large Caucasian pedigrees, we genotyped markers in eight chromosomal
regions previously reported as supporting linkage with type 2 diabetes. We previously …

Genetics of type 2 diabetes

I Barroso - Diabetic medicine, 2005 - Wiley Online Library
Abstract Type 2 diabetes (T2D) has become a health‐care problem worldwide, with the rise
in disease prevalence being all the more worrying as it not only affects the developed world …

A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population

MA Permutt, JC Wasson, BK Suarez, J Lin… - Diabetes, 2001 - Am Diabetes Assoc
A total of 896 individuals of Ashkenazi Jewish descent were ascertained in Israel from 267
multiplex families, including 472 sib-pairs affected with type 2 diabetes. A genome-wide …