New hydrazone derivatives were synthesized via the nucleophilic addition–elimination
reaction of 2-[(1-methyl-1H-tetrazol-5-yl) thio)] acetohydrazide with aromatic …

Background: In medicinal chemistry, thiazoles have gained great importance in antifungal
and anticancer drug design and development. Objectives: The aim of this study was to …

Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their
anticandidal activity using a broth microdilution assay. Among the synthesized compounds …

The increasing clinical importance of drug-resistant fungal pathogens has urged additional
need to fungal research and new antifungal compound development. For this purpose …

Novel (4-(4-iodophenyl)-thiazol-2-yl) hydrazine derivatives were assayed for their in vitro
anti-Candida activity, compared to topical and systemic antifungal drugs, against twenty …

In this study 18 new hydrazones have been synthesized by reacting ortho-or para-
substituted acetophenones with (3-substituted-1, 2, 4-triazol-5-yl-thio) acetohydrazide in …

Emerging yeasts are among the most prevalent causes of systemic infections with high
mortality rates and there is an urgent need to develop specific, effective and non-toxic …

Hydrazones are active compounds having an azomethine–NHN= CH group and are widely
studied owing to their ease of preparation and diverse pharmacological benefits. Novel …

Increase in the number of infections caused by pathogenic microbes in cancer patients has
prompted the searcher to invest in the development of agents having dual anticancer and …

In this study, 30 hydrazide–hydrazones of phenylacetic (3–10) and hydroxyacetic acid (11–
32) were synthesized by the condensation reaction of appropriate 2‐substituted acetic acid …