New Findings• What is the central question of this study? Does hypoxia enhance blood flow
to all parts of the brain uniformly?• What is the main finding and its importance? During …

The N2O technique was used in 6 human subjects to measure cerebral blood flow and
metabolism during hypoxia and hypercapnia induced by the inhalation of 10% O2-5% CO2 …

New Findings What is the central question of this study? In acute hypoxia, the reduction in
arterial CO2 tension due to the hypoxic ventilatory response (respiratory chemoreflex) …

The present study examined to what extent an acute bout of hypotension influences blood
flow in the external carotid artery (ECA) and the corresponding implications for blood flow …

The inability to quantify cerebral blood flow and changes in macrocirculation cross-sectional
area in all brain regions impedes robust insight into hypoxic cerebral blood flow control. We …

During acclimatization to the hypoxia of altitude, the cerebral circulation is exposed to
arterial hypoxia and hypocapnia, two stimuli with opposing influences on cerebral blood flow …

The postulation that hypoxia increases local cerebral blood flow (lCBF) mainly by perfusing
more capillaries (the capillary recruitment hypothesis) was tested in awake adult male …

In isolated rabbit common carotid, internal carotid, and basilar arteries denuded of
endothelium, mounted for measurement of contractile activity, and contracted with 10 …

Key points• The partial pressures of arterial carbon dioxide () and oxygen () has a marked
influence on brain blood flow.• It is unclear if the larger brain arteries are also sensitive to …

We examined 1) whether global cerebral blood flow (CBF) would increase across a 6-h bout
of normobaric poikilocapnic hypoxia and be mediated by a larger increase in blood flow in …