T-lymphocyte profile and total and virus-specific immunoglobulin concentrations in the cervix of HIV-1-infected women

AJ Quayle, AP Kourtis, S Cu-Uvin… - JAIDS Journal of …, 2007 - journals.lww.com
Background: The mucosal lymphocyte population is the largest in the body, and the
gastrointestinal compartment has been well characterized in HIV infection. Much less is …

Immunity in the female lower genital tract and the impact of HIV infection

SM Ahmed, H Al‐Doujaily, MA Johnson… - Scandinavian …, 2001 - Wiley Online Library
This study investigates the distribution of immunocompetent cells in the ectocervix, and
cytokine and immunoglobulin (Ig) levels in cervicovaginal secretions to determine whether …

Immunologic, virologic, and pharmacologic characterization of the female upper genital tract in HIV-infected women

L Rahangdale, K De Paris, ADM Kashuba… - JAIDS Journal of …, 2015 - journals.lww.com
A comparative analysis of cellular and soluble markers of immune activation in HIV-infected
women on combination antiretroviral therapy showed that the upper genital tract (UGT) …

Evaluation of immunologic markers in cervicovaginal fluid of HIV-infected and uninfected women: implications for the immunologic response to HIV in the female …

ES Beverly, RD D'Amico, AL Landay… - JAIDS Journal of …, 1997 - journals.lww.com
We analyzed 21 cervicovaginal lavage (CVL) specimens from 19 women participating in the
Women's Interagency HIV Study to characterize levels of antibody, cytokine, and …

Presence of CD8+ T Cells in the Ectocervical Mucosa Correlates with Genital Viral Shedding in HIV-Infected Women despite a Low Prevalence of HIV RNA …

A Gibbs, T Hirbod, Q Li, K Bohman, TB Ball… - The Journal of …, 2014 - journals.aai.org
The female genital tract is a portal of entry for sexual HIV transmission and a possible viral
reservoir. In this study, the ectocervical CD8+ T cell distribution was explored in situ and was …

Changes to the cytokine microenvironment in the genital tract mucosa of HIV+ women

Olaitan, Reid, Poulter - Clinical & Experimental Immunology, 1998 - Wiley Online Library
As previous studies have indicated that genital tract mucosal T cell function may be impaired
in HIV infection, we investigated the T cell cytokine mRNA in the genital tract mucosa of HIV …

The distribution of immunocompetent cells in the genital tract of HIV-positive women

A Olaitan, MA Johnson, A MacLean, LW Poulter - Aids, 1996 - journals.lww.com
Objective: To study the distribution of immunocompetent cells in the female lower genital
tract and to determine whether it is altered in HIV infection. Methods: Colposcopically …

Immune activation in the female genital tract during HIV infection predicts mucosal CD4 depletion and HIV shedding

HB Jaspan, L Liebenberg, W Hanekom… - Journal of Infectious …, 2011 - academic.oup.com
Plasma viral load predicts genital tract human immunodeficiency virus (HIV) shedding in HIV-
infected women. We investigated whether local mucosal T-cell activation (HLA-DR, CD38 …

Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tract

NN Nkwanyana, PP Gumbi, L Roberts, L Denny… - …, 2009 - Wiley Online Library
Cervical cytobrush sampling is a relatively non‐invasive method for obtaining mucosal cells
from the female genital tract. To define mucosal immune cells sampled by cervical …

Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1–resistant Kenyan commercial sex workers

SM Iqbal, TB Ball, J Kimani, P Kiama… - The Journal of …, 2005 - academic.oup.com
The initial site of exposure to human immunodeficiency virus (HIV)–1 during heterosexual
transmission occurs in the genital tract. Although the majority of immunological studies have …