Cannabinoid receptors and their ligands play significant roles in regulating bone
metabolism. Previous studies of type 1 cannabinoid receptor-deficient mice have shown that …

Previous studies have shown that the skeletal consequences of cannabinoid receptor
deficiency differ in different strains of mice. In order to explore the mechanisms responsible …

Recent studies have shown that the endocannabinoid system plays a key role in regulating
bone formation and bone resorption. It has been also reported that mice with deficiency of …

The endocannabinoid system plays a role in regulating bone mass and bone cell activity
and inactivation of the type 1 (Cnr1) or type 2 (Cnr2) cannabinoid receptors influences peak …

The CB1 cannabinoid receptor has been implicated in the regulation of bone remodeling
and bone mass. A high bone mass (HBM) phenotype was reported in CB1-null mice …

The type 2 cannabinoid receptor (CB2) has been reported to regulate bone mass and bone
turnover but the mechanisms responsible are incompletely understood. In this study we …

Osteoporosis is one of the most common degenerative diseases. It is characterized by
reduced bone mineral density (BMD) with an increased risk for bone fractures. There is a …

The endocannabinoid system has recently been shown to play a role in the regulation of
bone metabolism. The type 2 cannabinoid receptor (CB2) has been reported to regulate …

The endocannabinoid system is recognized to play an important role in regulating a variety
of physiological processes, including appetite control and energy balance, pain perception …

The endocannabinoid (eCB) system, including its receptors, ligands, and their metabolizing
enzymes, plays an important role in bone physiology. Skeletal cannabinoid type 1 (CB1) …