Cytokines are a large family of more than 100 small proteins that function as short-range
mediators involved in essentially all biological processes. They have been found to be …

Cytokines are small, secreted proteins associated with the maintenance of immune
homeostasis but also implicated with the pathogenesis of several autoimmune and …

Commentary Page 1 Immunity Commentary Cytokines as Therapeutic Targets: Advances and
Limitations Clemens Scheinecker,1 Kurt Redlich,1 and Josef S. Smolen1,* 1Division of …

Inflammatory conditions in some tissues increase the risk of cancer. Cytokines and
chemokines are components of an intensive dialog promoting angiogenesis, metastasis …

During the past 40 years, cytokines and cytokine receptors have been extensively
investigated as either cancer targets or cancer treatments. A strong preclinical rationale …

Pathogens or genotoxic agents continuously affect the human body. Acute inflammatory
reaction induced by a non-sterile or sterile environment is triggered for the efficient …

Simple Summary Cytokines are important molecular players in cancer development,
progression, and potential targets for treatment. Despite being small and overlooked …

Cytokine research has spawned the introduction of new therapies that have revolutionized
the treatment of many important diseases. These therapeutic advances have resulted from …

Cancer has long been considered a disease that is associated with immune tolerance. Its
connection with inflammation initially appears paradoxical. During the last decade, it has …

Cytokines such as IL-1 and TNF are primarily pro-inflammatory. The inflammation induced
by these cytokines is reflected in the type of genes they induce. In the pathogenesis of …