Drug-in-hydroxypropyl-β-cyclodextrin-in-lipoid S100/cholesterol liposomes: Effect of the characteristics of essential oil components on their encapsulation and release

Z Hammoud, R Gharib, S Fourmentin… - International Journal of …, 2020 - Elsevier
Abstract Drug-in-cyclodextrin-in-liposome (DCL) represents a very promising approach for
preserving essential oil (EO) components, thereby extending their shelf life and activity. In …

Drug-in-cyclodextrin-in-liposomes as a carrier system for volatile essential oil components: Application to anethole

R Gharib, L Auezova, C Charcosset, H Greige-Gerges - Food chemistry, 2017 - Elsevier
A combined approach based on cyclodextrin/drug inclusion complex formation and loading
into liposomes was applied to improve the effectiveness of liposome loading with essential …

[HTML][HTML] Encapsulation of α-pinene in delivery systems based on liposomes and cyclodextrins

Z Hammoud, M Kayouka, A Trifan, E Sieniawska… - Molecules, 2021 - mdpi.com
The essential oil component α-pinene has multiple biological activities. However, its
application is limited owing to its volatility, low aqueous solubility, and chemical instability …

Clove essential oil-in-cyclodextrin-in-liposomes in the aqueous and lyophilized states: From laboratory to large scale using a membrane contactor

C Sebaaly, C Charcosset, S Stainmesse, H Fessi… - Carbohydrate …, 2016 - Elsevier
This work is dedicated to prepare liposomal dry powder formulations of inclusion complexes
of clove essential oil (CEO) and its main component eugenol (Eug). Ethanol injection …

New findings on the incorporation of essential oil components into liposomes composed of lipoid S100 and cholesterol

Z Hammoud, R Gharib, S Fourmentin… - International journal of …, 2019 - Elsevier
The encapsulation of essential oil components into liposomes was demonstrated to improve
their solubility and chemical stability. In this study, we investigated the effect of chemical …

First evaluation of drug-in-cyclodextrin-in-liposomes as an encapsulating system for nerolidol

J Azzi, L Auezova, PE Danjou, S Fourmentin… - Food chemistry, 2018 - Elsevier
Nerolidol, a naturally occurring sesquiterpene with antimicrobial activities, is a promising
candidate as a natural alternative for synthetic preservatives in food. However, its …

Novel findings for quercetin encapsulation and preservation with cyclodextrins, liposomes, and drug-in-cyclodextrin-in-liposomes

J Azzi, A Jraij, L Auezova, S Fourmentin… - Food …, 2018 - Elsevier
The low solubility, poor bioavailability, and low chemical stability of quercetin (Quer) are the
main drawbacks that limit its use as a food nutraceutical. In this study, the encapsulation in …

[HTML][HTML] Cyclodextrins-in-Liposomes: A Promising Delivery System for Lippia sidoides and Syzygium aromaticum Essential Oils

I Baldim, AM Oliveira, EB Souto, WP Oliveira - Life, 2022 - mdpi.com
Biological activity of essential oils (EOs) has been extensively reported; however, their low
aqueous solubility, high photosensitivity, and volatility compromise a broad industrial use of …

Retention of Eucalyptol, a Natural Volatile Insecticide, in Delivery Systems Based on Hydroxypropyl‐β‐Cyclodextrin and Liposomes

R Gharib, JMB Jemâa, C Charcosset… - European journal of …, 2020 - Wiley Online Library
Eucalyptol (Euc) is a natural monoterpene with insecticide effects. Being highly volatile and
sensitive to ambient conditions, its encapsulation would enlarge its application. Euc‐loaded …

Drug-in-cyclodextrin-in-liposomes: A promising delivery system for hydrophobic drugs

J Chen, WL Lu, W Gu, SS Lu, ZP Chen… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Recently, the entrapment of hydrophobic drugs in the form of water-soluble
drug–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to …