[HTML][HTML] Dosing and formulation of antenatal corticosteroids for fetal lung maturation and gene expression in rhesus macaques

AF Schmidt, PS Kannan, JP Bridges, A Filuta, D Lipps… - Scientific reports, 2019 - nature.com
Antenatal corticosteroids (ANS) are the major intervention to decrease respiratory distress
syndrome and mortality from premature birth and are standard of care. The use of ANS is …

[HTML][HTML] Oral dosing for antenatal corticosteroids in the Rhesus macaque

AF Schmidt, MW Kemp, M Milad, LA Miller, JP Bridges… - PloS one, 2019 - journals.plos.org
Antenatal corticosteroids (ACS) are standard of care for women at risk of preterm delivery,
although choice of drug, dose or route have not been systematically evaluated. Further, ACS …

[HTML][HTML] Antenatal corticosteroids: a reappraisal of the drug formulation and dose

AH Jobe, M Kemp, A Schmidt, T Takahashi… - Pediatric …, 2021 - nature.com
We review the history of antenatal corticosteroid therapy (ACS) and present recent
experimental data to demonstrate that this, one of the pillars of perinatal care, has been …

Antenatal corticosteroid therapy: current strategies and identifying mediators and markers for response

N Falah, DM Haas - Seminars in Perinatology, 2014 - Elsevier
Landmark early work has led to the nearly universal use of antenatal corticosteroids to
accelerate fetal lung maturity with pregnancies complicated by impending preterm birth …

Antenatal corticosteriods decrease forced vital capacity in infants born fullterm

A Bandyopadhyay, JE Slaven, C Evrard… - Pediatric …, 2020 - Wiley Online Library
Antenatal corticosteroids (ACS) administration to pregnant women for threatened preterm
labor is standard obstetric care to reduce neonatal respiratory distress syndrome and the …

Optimizing antenatal corticosteroid therapy

MW Kemp, AF Schmidt, AH Jobe - Seminars in Fetal and Neonatal …, 2019 - Elsevier
Abstract Treatment with antenatal corticosteroids (ACS) is standard of care for women at risk
of preterm birth between 24 and 34 weeks' gestation. ACS are increasingly used for other …

[HTML][HTML] Oral antenatal corticosteroids evaluated in fetal sheep

AF Schmidt, AH Jobe, PS Kannan, JP Bridges… - Pediatric …, 2019 - nature.com
Background The use of antenatal corticosteroids (ACS) in low-resource environments is
sporadic. Further, drug choice, dose, and route of ACS are not optimized. We report the …

Prenatal corticosteroids—early gain, long-term questions

AD Stiles - New England Journal of Medicine, 2007 - Mass Medical Soc
A single course of prenatal corticosteroid therapy has been shown to accelerate fetal lung
maturation when premature delivery is imminent. 1–3 This therapy reduces morbidity and …

[HTML][HTML] Low-dose antenatal betamethasone treatment achieves preterm lung maturation equivalent to that of the World Health Organization dexamethasone regimen …

H Usuda, EL Fee, S Carter, L Furfaro… - American Journal of …, 2022 - Elsevier
Background The intramuscular administration of antenatal steroids to women at risk of
preterm delivery achieves high maternal and fetal plasma steroid concentrations, which are …

Antenatal corticosteroids: we continue to learn

R Wapner - American Journal of Obstetrics & Gynecology, 2004 - ajog.org
National Institute of Child Health and Development consensus panels held in 1994 and
2000 concluded that both betamethasone and dexamethasone accelerated fetal lung …