Abstract Lessons Learned Novaferon showed moderate efficacy and was well-tolerated in
patients with metastatic colorectal cancer (mCRC), especially with the 20 μg injected 3 times …

Aim: The combination of a peptide vaccine and tegafur-uracil plus leucovorin (UFT/LV) were
evaluated in patients with metastatic colorectal cancer refractory to standard chemotherapy …

4048 Background: PolyPEPI1018 is an off-the-shelf, multi-peptide vaccine containing 12
immunogenic epitopes derived from 7 cancer testis antigens (CTAs) frequently expressed in …

To test the safety and immune responses of a novel peptide vaccine derived from RNF43
(ring finger protein 43) and TOMM34 (34-kDa translocase of the outer mitochondrial …

BACKGROUND: Colorectal cancer remains one of the leading causes of death in the world.
Surgery still remains the mainstay of treatment for primary and metastatic colorectal cancer …

Background AVX701 is an alphaviral replicon particle vaccine expressing a modified
carcinoembryonic antigen gene (CEA (6D)). We previously reported the preliminary results …

Phase I study of combination therapy with peptide vaccine and anti-cancer drug for
colorectal cancer has been performed in our hospital. The purpose of this study was to …

Colorectal cancer (CRC) is one of the most common malignant tumors in the world, which is
also the main death cause of cancer patients. Surgery, radiotherapy and chemotherapy can …

Monoclonal antibodies (MAbs) have different modes of action and toxicity profile compared
to chemotherapeutics, which makes it interesting to combine these drugs. Addition of …

To investigate the safety and immunological responses of personalized peptide vaccination
in combination with oral administration of UFT and UZEL for metastatic colorectal carcinoma …