Docosahexaenoic acid (DHA) is an essential component for brain development during fetal
and early postnatal life. Hyperbilirubinemia is characterized by abnormally high levels of …

Usually, all newborns demonstrate high serum unconjugated bilirubin (UCB) level. UCB
may induce adverse effects in the central nervous system. We aimed to evaluate the …

Background: The pathophysiology of bilirubin neurotoxicity in course of hypoxic–ischemic
encephalopathy (HIE) in term and preterm infants is still poorly understood. We …

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the causes of severe
hyperbilirubinemia, prolonged jaundice, and bilirubin-induced encephalopathy in neonates …

Aim This study aimed to investigate the effect of adding ursodeoxycholic acid (UDCA) to
phototherapy in neonates with glucose‐6‐phosphate dehydrogenase (G6PD) deficiency …

All pre-term newborns and a high proportion of term newborns develop neonatal jaundice.
Neonatal jaundice is usually a benign condition and self-resolves within few days after birth …

Background Bilirubin encephalopathy is a serious complication in neonatal jaundice and is
associated with high mortality and disability in newborns. The present study aimed to …

Background: Ursodeoxycholic acid (UDCA) is a safe drug used in the treatment of
cholestatic liver disorders in children. The aim of this study was to investigate the synergistic …

J. Neurochem.(2010) 112, 56–65. Abstract High levels of unconjugated bilirubin (UCB) may
initiate encephalopathy in neonatal life, mainly in pre‐mature infants. The molecular …

Neonatal jaundice or hyperbilirubinemia is the result of alterations in the bilirubin
metabolism. Prolonged and uncontrolled high levels of unconjugated bilirubin lead to …