[HTML][HTML] The “hook effect” causing a negative pregnancy test in a patient with an advanced molar pregnancy

AD Winder, AS Mora, E Berry, JR Lurain - Gynecologic oncology reports, 2017 - Elsevier
Highlights•At high hCG levels in molar pregnancies, a “hook effect” can cause an artificially
negative value.•Delay in diagnosis of a molar pregnancy due to the “hook effect” can lead to …

[PDF][PDF] Molar pregnancy with false negative urine hCG: the hook effect

YP Pang, H Rajesh, LK Tan - Singapore Med J, 2010 - smj.org.sg
Urine pregnancy tests are widely used in emergency departments as the first screening test
for patients of reproductive age presenting with gynaecological problems in order to rule out …

Qualitative β-hCG urine assays may be misleading in the presence of molar pregnancy: a case report

CM Davison, RM Kaplan, LN Wenig… - The Journal of emergency …, 2004 - Elsevier
Molar pregnancy is a rare complication of pregnancy and the diagnosis is usually confirmed
with a markedly elevated β-hCG and a “snowstorm” appearance on pelvic ultrasound …

[HTML][HTML] Abnormally low hCG in a complete hydatidiform molar pregnancy: the hook effect

JL Nodler, KH Kim, RD Alvarez - Gynecologic Oncology Case …, 2011 - ncbi.nlm.nih.gov
Hydatidiform molar pregnancy occurs as a proliferative disorder of trophoblastic cells.
Complete hydatidiform moles present with abnormally high levels of human chorionic …

Low risk of relapse after achieving undetectable HCG levels in women with partial molar pregnancy

AJ Wolfberg, WB Growdon, CM Feltmate… - Obstetrics & …, 2006 - journals.lww.com
OBJECTIVE: We evaluated the risk of gestational trophoblastic neoplasia (GTN) for women
with partial molar pregnancy whose human chorionic gonadotropin (hCG) levels fall …

Human chorionic gonadotropin follow-up in patients with molar pregnancy: a time for reevaluation

CM Feltmate, J Batorfi, V Fulop… - Obstetrics & …, 2003 - journals.lww.com
OBJECTIVE To determine how often patients with molar pregnancy do not complete
recommended follow-up and to identify factors that may predict failure to complete human …

Regression of hCG in various types of molar pregnancies--clinical course and prognosis

L Rob, H Robova, M Pluta, E Kulovaný… - Ceska …, 2001 - europepmc.org
Objective To evaluate spontaneous regression curves of hCG serum positivity in patients
with surgically treated molar pregnancies. Comparison of complete, partial and invasive …

Low risk of relapse after achieving undetectable HCG levels in women with complete molar pregnancy

AJ Wolfberg, C Feltmate, DP Goldstein… - Obstetrics & …, 2004 - journals.lww.com
OBJECTIVE: Complete hydatidiform molar pregnancies occur in approximately 1 of 1,000
conceptions. After uterine evacuation of the trophoblastic tissue, women are followed up with …

“Hook effect” in complete hydatidiform molar pregnancy: A falsely low level of β-hCG

H Levavi, A Neri, J Bar, D Regev… - Obstetrics & …, 1993 - journals.lww.com
Background: In some cases of gestational trophoblastic disease, a large amount of serum
[beta]-hCG may lead to the high-dose" hook effect" with falsely low serum levels, creating …

[HTML][HTML] Molar pregnancy with false negative β-hCG urine in the emergency department

CL Hunter, J Ladde - Western Journal of Emergency Medicine, 2011 - ncbi.nlm.nih.gov
This case describes an atypical presentation of molar pregnancy in an emergency
department patient with abdominal pain and vaginal bleeding. The patient demonstrated …