Hyperoxia (HO)-induced lung injury contributes to bronchopulmonary dysplasia (BPD) in
preterm newborns. Intractable wheezing seen in BPD survivors is associated with airway …

Bronchopulmonary dysplasia of the premature newborn is characterized by lung injury,
resulting in alveolar simplification and reduced pulmonary function. Exposure of neonatal …

Abstract Background Sphingosine-1-Phosphate (S1P) is a bioactive lipid and an
intracellular as well as an extracellular signaling molecule. S1P ligand specifically binds to …

Introduction Neonatal lung injury as a consequence of hyperoxia (HO) therapy and ventilator
care contribute to the development of bronchopulmonary dysplasia (BPD). Increased …

Introduction We have earlier shown that hyperoxia (HO)-induced sphingosine kinase 1
(SPHK1)/sphingosine-1-phosphate (S1P) signaling contribute to bronchopulmonary …

Bronchopulmonary dysplasia (BPD), a common complication of preterm birth, is associated
with pulmonary hypertension (PH) in 25% of infants with moderate to severe BPD. Neonatal …

Background Bronchopulmonary dysplasia (BPD) is a major morbidity in premature infants,
and impaired angiogenesis is considered a major contributor to BPD. Early caffeine …

The pathological hallmarks of bronchopulmonary dysplasia (BPD), a chronic lung disease of
premature infants, include inflammation, arrested alveolarization, and dysregulated …

Premature infants are born with developing lungs burdened by surfactant deficiency and a
dearth of antioxidant defense systems. Survival rate of such infants has significantly …

Despite tremendous technological and therapeutic advances, bronchopulmonary dysplasia
(BPD) remains a leading cause of respiratory morbidity in very low birth weight infants, and …