Opioids act at μ-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance
MD Loose, MJ Kelly - Brain research, 1990 - Elsevier
Intracellular recordings were made from 48 hypothalamic arcuate (ARC) neurons under
current-and voltage-clamp in slices prepared from female guinea pigs which had been …
current-and voltage-clamp in slices prepared from female guinea pigs which had been …
Opioids hyperpolarize β-endorphin neurons via μ-receptor activation of a potassium conductance
MJ Kelly, MD Loose, OK Ronnekleiv - Neuroendocrinology, 1990 - karger.com
Intracellular recordings were made from hypothalamic arcuate (ARC) neurons with biocytin-
filled electrodes under current-and voltage-clamp in slices prepared from ovariectomized …
filled electrodes under current-and voltage-clamp in slices prepared from ovariectomized …
Neurons in the Rat Arcuate Nucleus Are Hyperpolarized by GABAB and μ-Opioid Receptor Agonists: Evidence for Convergence at a Ligand-Gated Potassium …
MD Loose, OK Ronnekleiv, MJ Kelly - Neuroendocrinology, 1991 - karger.com
Both γ-aminobutyric acid (GABA) and the endogenous opioid peptides have pervasive
effects on neuroendocrine function. This study examined the effects of selective activation of …
effects on neuroendocrine function. This study examined the effects of selective activation of …
The potency of mu-opioid hyperpolarization of hypothalamic arcuate neurons is rapidly attenuated by 17 beta-estradiol
AH Lagrange, OK Ronnekleiv… - Journal of Neuroscience, 1994 - Soc Neuroscience
The mu-opioid agonist DAMGO (Tyr-D-Ala-Gly-MePhe-Gly-ol) hyperpolarizes the majority of
arcuate hypothalamic (ARC) neurons by opening an inwardly rectifying potassium …
arcuate hypothalamic (ARC) neurons by opening an inwardly rectifying potassium …
Hyperpolarization by opioids acting on μ‐receptors of a sub‐population of rat periaqueductal gray neurones in vitro
B Chieng, MJ Christie - British journal of pharmacology, 1994 - Wiley Online Library
1 The actions of opioids on membrane properties of rat periaqueductal gray neurones were
investigated using intracellular recordings from single neurones in brain slices …
investigated using intracellular recordings from single neurones in brain slices …
Direct effects of an opioid peptide selective for μ-receptors: intracellular recordings in the paraventricular and supraoptic nuclei of the guinea-pig
JP Wuarin, FE Dudek - Neuroscience, 1990 - Elsevier
Abstract Responses to [d-Ala 2, MePhe 4, Gly-ol 5] enkephalin, a selective agonist for μ-
receptors, were recorded intracellularly from 26 neurons in slices of guinea-pig …
receptors, were recorded intracellularly from 26 neurons in slices of guinea-pig …
Estrogen suppresses mu-opioid-and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons
MJ Kelly, MD Loose, OK Ronnekleiv - Journal of Neuroscience, 1992 - Soc Neuroscience
The effects of estrogen on the response of hypothalamic arcuate neurons to mu-opioid and
GABAB agonists were investigated. Intracellular recordings were made from arcuate …
GABAB agonists were investigated. Intracellular recordings were made from arcuate …
Membrane properties and response to opioids of identified dopamine neurons in the guinea pig hypothalamus
MD Loose, OK Ronnekleiv, MJ Kelly - Journal of Neuroscience, 1990 - Soc Neuroscience
The electrophysiological properties and opioid responsiveness of the dopamine-containing
neurons in the arcuate nucleus of the guinea pig hypothalamus were examined. Dopamine …
neurons in the arcuate nucleus of the guinea pig hypothalamus were examined. Dopamine …
κ‐Opioid receptor‐mediated enhancement of the hyperpolarization‐activated current (Ih) through mobilization of intracellular calcium in rat nucleus raphe magnus
ZZ Pan - The Journal of Physiology, 2003 - Wiley Online Library
The hyperpolarization‐activated current (Ih) is important in the control of resting membrane
potential, in the regulation of network firing pattern and in the modulation of presynaptic …
potential, in the regulation of network firing pattern and in the modulation of presynaptic …
Tolerance of hypothalamic beta-endorphin neurons to mu-opioid receptor activation after chronic morphine.
GE Zhang, AH Lagrange, OK Rønnekleiv… - Journal of Pharmacology …, 1996 - ASPET
The mu-opioid receptor is an autoreceptor on hypothalamic beta-endorphin neurons that
when activated inhibits cell firing via increasing an inwardly rectifying potassium …
when activated inhibits cell firing via increasing an inwardly rectifying potassium …