Intermediate test results often occur with diagnostic tests. When assessing diagnostic
accuracy, it is important to properly report and account for these results. In the literature …

OBJECTIVE: In diagnostic accuracy studies, the reference standard may be imperfect or not
available in all patients. We systematically reviewed the proposed solutions for these …

When no gold standard is available to evaluate a diagnostic or screening test, as is often the
case, an imperfect reference standard test must be used instead. Furthermore, the errors of …

Background A common feature of diagnostic research is that results for a diagnostic gold
standard are available primarily for patients who are positive for the test under investigation …

Methods for standard meta‐analysis of diagnostic test accuracy studies are well established
and understood. For the more complex case in which studies report test accuracy across …

Performance of a diagnostic test is ideally evaluated by a comparison of the test results to a
gold standard for all the patients in a study. In practice, however, it is common for a subset of …

Obtaining accurate estimates of the performance of a diagnostic test for some population of
patients might be difficult when the sample of subjects used for this purpose is not …

Detection and Diagnostic Overall Accuracy Measures of Medical Tests - PMC Back to Top Skip
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Background: In diagnostic accuracy studies, index test results are verified by comparing
them with results of the reference standard. In some studies there is partial verification, when …

There is a wide body of literature in biostatistics and epidemiology literature about
estimating diagnostic accuracy, such as sensitivity and specificity of a binary test, without a …