The production of nitric oxide (NO) from l-arginine is catalyzed by NO synthase (NOS), which
exists as the following three isoforms: endothelial (eNOS), neuronal (nNOS), and inducible …

Our study was designed to determine involvement of nitric oxide (NO) in the antinociception
mediated by mu, delta andkappa opioid receptors in acute and prolonged pain in the rat …

Abstract N‐palmitoyl‐ethanolamine (PEA) is an endogenous substance that was first
identified in lipid tissue extracts. It has been classified as a CB2 receptor agonist …

The aim of this study is to investigate the involvement of nitric oxide synthesized by the
inducible (NOS2) or neuronal (NOS1) nitric oxide synthases in the local antinociceptive …

The nitric oxide synthase (NOS) inhibitor t,-nitroarginine methyl ester has been found to
exhibit antinociceptive activity in a rat model of pain [Kitto, KF et al., Neurosci. Lett., 148 …

Purpose To assess the systemic and nociceptive effects of nitric oxide synthase (NOS)
inhibitors in the modulation of acute pain in rats subjected to the formalin test. Methods …

Abstract N G-nitro-L-arginine methyl ester (L-NAME, 400–1500μg), administered
intrathecally (ith.), elicits a slight but dose-related antinociception in rats, assessed by tail …

Previous studies have implicated nitric oxide (NO) in the antinociceptive response to the
anesthetic gas nitrous oxide (N2O). The present study was conducted to confirm this NO …

Acute tissue damage is accompanied by synthesis of nitric oxide (NO) in the inflamed tissue
as well as in the spinal cord. NO release at the spinal level is likely involved in the …

Nitric oxide (NO) donors (SIN-1, SNAP, hydroxylamine, given ith.) induced hyperalgesia in
rats, while, in contrast, the inhibitor of nitric oxide synthase L-NAME (ith. or icv) elicited …