The present paper reviews evidence on the effect of antidepressant treatments on dopamine
transmission. Chronic treatment with antidepressant drugs potentiates the behavioural …

The effect of the selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor,
fluoxetine (10 mg/kg sc), two tricyclic antidepressants, clomipramine (10 mg/kg sc) and …

This paper reviews the effects of antidepressants on brain dopamine (DA) function in people
and animals. Acute antidepressant treatments have no consistent effect on DA. Chronic …

Drugs differing in their primary mechanism of action but having in common the ability to act
as antidepressants such as fluoxetine (10 mg/kg SC), clomipramine (10 mg/kg IP) …

Chronic treatment with antidepressant drugs produces a variety of changes in dopaminergic
neurotransmission. most notably a sensitization of behavioural responses to agonists acting …

Clinical studies have not yet determined a common mechanism of action for antidepressant
drugs, which have primary sites of action on a variety of different neurotransmitter systems …

A series of experiments was performed to evaluate the mechanism (s) by which chronic
administration of desipramine (DMI) facilitates the locomotor stimulant action of d …

Several hypotheses regarding the physiopathology of major depression exist. Attention has
been focused on cerebral monoaminergic systems, the dysfunction of which is thought to …

The relationship between depression and dopamine deficiency in the mesolimbic pathway
has been hypothesized for many years. The experimental studies with animal models of …

The effects of acute and chronic administration of desipramine (DMI) on a number of
behaviors thought to be dependent on central dopaminergic (DA) systems were examined in …