Sepsis and septic shock are among the leading causes of death in intensive care units
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …

Review on sepsis mediators, and roles in innate and adaptive immune systems, as well as
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …

Sepsis is a devastating and complex syndrome and continues to be a major cause of
morbidity and mortality among critically ill patients at the surgical intensive care unit setting …

Background: Sepsis is a serious clinical condition characterized by damage to the immune
system as a result of an uncontrolled response to infection. Septic patients show …

Sepsis is currently defined as a life-threatening organ dysfunction caused by a dysregulated
host response to infection, and it affects over 25 million people every year. Even more …

Sepsis is a life-threatening medical condition that occurs when the host has an uncontrolled
or abnormal immune response to overwhelming infection. It is now widely accepted that …

Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Sepsis is known since the time (470 BC) of great Greek physician, Hippocrates.
Advancement in modern medicine and establishment of separate branches of medical …

Sepsis is a leading cause of death worldwide. After initial trials modulating the
hyperinflammatory phase of sepsis failed, generations of researchers have focused on …

Sepsis with subsequent multiple organ dysfunction is a pronounced systemic inflammatory
response to concealed or known infection and is a leading cause of death in intensive care …