The GATA family of vertebrate DNA binding regulatory proteins are expressed in diverse
tissues and at different times of development. However, the DNA binding regions of these …

GATA-1 and other vertebrate GATA factors contain a DNA binding domain composed of two
adjacent homologous zinc fingers. Whereas only the C-terminal finger of GATA-1 is capable …

The GATA family of transcription factors (GATA1–6) binds selected GATA sites in vertebrate
genomes to regulate specific gene expression. Although vertebrate GATA factors have two …

Mammalian GATA transcription factors are expressed in various tissues in a temporally
regulated manner. The prototypic member, GATA-1, is required for normal erythroid …

We have generated and analyzed by functional assays mutations of the chicken erythroid
transcription factor GATA-1. The cGATA-1 protein contains two related finger domains highly …

GATA-binding proteins constitute a family of transcription factors that recognize a target site
conforming to the consensus WGATAR (W= A or T and R= A or G). Here we have used the …

We used a one-hybrid system to replace precisely the finger II chicken GATA-1 DNA-binding
domain with the binding domain of bacterial repressor protein LexA. The LexA DNA-binding …

The GATA‐1 transcription factor has been shown to be important in the regulation of globin
and non‐globin genes in erythroid, megakaryocytic and mast cell lineages. It is a member of …

GATA-1, a transcription factor essential for the development of the erythroid lineage,
contains two adjacent highly conserved zinc finger motifs. The carboxy-terminal finger is …

Zinc fingers are recognized as small protein domains that bind to specific DNA sequences.
Recently however, zinc fingers from a number of proteins, in particular the GATA family of …