Reduced structural proteins in the conjunctival epithelium in allergic eye disease

JL Hughes, PM Lackie, SJ Wilson, MK Church… - Allergy, 2006 - Wiley Online Library
Aims: Allergic eye disease affects up to 20% of the population with varying severity. The
conjunctival epithelium plays a key role in allergic eye disease. The purpose of this study …

The role of the conjunctival epithelium in ocular allergy

M Calonge… - Current opinion in allergy …, 2005 - journals.lww.com
The ocular surface epithelium is not just a simple physical barrier to the entrance of foreign
bodies. It participates in the allergic inflammatory process by being influenced by …

The role of conjunctival epithelial cells in chronic ocular allergic disease

M HINGORANI, VL CALDER, RJ BUCKLEY… - Experimental eye …, 1998 - Elsevier
Recent evidence suggests that mucosal epithelial cells are capable of actively participating
in immune reactions via expression of surface antigens, such as adhesion molecules, and …

Adhesion molecules and relationship to leukocyte levels in allergic eye disease.

AS Bacon, JI McGill, DF Anderson… - … & visual science, 1998 - iovs.arvojournals.org
PURPOSE: To evaluate the conjunctival expression of leukocyte cell adhesion molecules
(CAMs) and their relationship to leukocyte patterns on the microvasculature in the different …

Correlation between tear IgE levels and HLA-DR expression by conjunctival cells in allergic and nonallergic chronic conjunctivitis

C Baudouin, T Bourcier, F Brignole, F Bertel… - Graefe's archive for …, 2000 - Springer
Background: Chronic conjunctival inflammatory diseases may depend upon various
mechanisms. Discriminating allergy from nonspecific inflammation has become of striking …

Basic science and pathophysiology of ocular allergy

VL Calder, PM Lackie - Current Allergy and Asthma Reports, 2004 - Springer
Ocular allergy includes several clinical subtypes ranging from the mild seasonal allergic
conjunctivitis to the potentially sight-threatening atopic keratoconjunctivitis. Current …

Immunopathogenesis of chronic allergic conjunctivitis

KF Tabbara - International ophthalmology clinics, 2003 - journals.lww.com
Several cells and mediators play a role in the immunopathogenesis of ocular allergy, and a
cascade of chemical mediators and reactions is involved. Conjunctival biopsy specimens of …

Increased conjunctival expression of protease activated receptor 2 (PAR-2) in seasonal allergic conjunctivitis: a role for abnormal conjunctival epithelial permeability …

S Yeoh, M Church, P Lackie, J McGill, M Mota… - British journal of …, 2011 - bjo.bmj.com
Aims Aeroallergen exposure to the conjunctival epithelium in seasonal allergic conjunctivitis
(SAC) may induce a cellular stress response that disrupts the barrier properties of the …

Alterations of the ocular surface epithelial mucins 1, 2, 4 and the tear functions in patients with atopic keratoconjunctivitis

M Dogru, N Okada, N Asano‐Kato… - Clinical & …, 2006 - Wiley Online Library
Background An increased understanding of the ocular surface alterations at the cellular
level in the conjunctiva and the cornea, may help explain the pathogenesis and the …

Molecular and cellular aspects of allergic conjunctivitis

G Liu, A Keane-Myers, D Miyazaki, A Tai… - Chemical …, 1999 - books.google.com
One of the most common immunologically mediated diseases of the eye is allergic
conjunctivitis (AC). Over 14% of the population of the USA suffers from some form of this …