In the present study, we examine rod photoreceptor development in dissociated-cell cultures
of neonatal mouse retina. We show that, although very few rhodopsin+ rods develop in the …

purpose. Activating ligands of gp130, including leukemia inhibitory factor (LIF), can block
differentiation and function of retinal neurons. This study focused on determining whether …

We have conducted a comprehensive analysis of the relative timing of the terminal mitosis
and the onset of rhodopsin expression in rod precursors in the rat retina in vivo. This …

Leukemia inhibitory factor (LIF), an interleukin-6 family neurocytokine, is up-regulated in
response to different types of retinal stress and has neuroprotective activity through …

The retina is a relatively simple and well-characterized CNS structure in which cell-cell
interactions have been hypothesized to influence cell type determination. By manipulating …

Photoreceptors are the most abundant cell type in the vertebrate neural retina. Like the other
retinal neurons and the Müller glia, they arise from a population of precursor cells that are …

Retinoids, vitamin A (retinol) and its metabolic derivatives, are required for normal vertebrate
development. In murine embryonic stem (ES) cells, which remain undifferentiated when …

purpose. The purpose of this study was to determine the intracellular pathways by which
ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF) negatively regulate the …

We previously developed a reaggregate cell culture system in which embryonic rat retinal
neuroepithelial cells proliferate and give rise to opsin-expressing rod photoreceptor cells …

Purpose: Vascular development in the eye has been described as a complex process
involving both vasculogenesis and angiogenesis. Multiple cell types are involved in the …