The incidence of hearing impairment (HI) is higher in low-and middle-income countries
when compared to high-income countries. There is therefore a necessity to estimate the …

Introduction Hearing impairment (HI) is characterized by complex genetic heterogeneity. The
evolution of next generation sequencing, including targeted enrichment panels, has …

Hearing impairment (HI) is highly heterogeneous with over 123 associated genes reported
to date, mostly from studies among Europeans and Asians. Here, we performed a systematic …

We investigated hearing impairment (HI) in 51 families from Ghana with at least two affected
members that were negative for GJB2 pathogenic variants. DNA samples from 184 family …

Hearing loss is the most common sensorineural disorder worldwide and is associated with
more than 1000 mutations in more than 90 genes. While mutations in genes such as GJB2 …

Hearing impairment (HI) is a silent planetary health crisis that requires attention worldwide.
The prevalence of HI in South Africa is estimated as 5.5 in 100 live births, which is about 5 …

The past 30 years have seen an exponential growth concerning the identification of genes
and variants responsible for hereditary hearing loss (HL) worldwide. This has led to a huge …

This study aimed to investigate GJB2 (connexin 26) and GJB6 (connexin 30) mutations
associated with familial non-syndromic childhood hearing impairment (HI) in Cameroon. We …

This study aimed to investigate GJB2 (connexin 26) and GJB6 (connexin 30) mutations
associated with familial non-syndromic childhood hearing impairment (HI) in Cameroon. We …

Objective To systematically assess the data on the prevalence and causes of hearing
impairment in Africa. Methods Systematic review on the prevalence and causes of hearing …