[HTML][HTML] Glycoproteogenomics: A Frequent Gene Polymorphism Affects the Glycosylation Pattern of the Human Serum Fetuin/α-2-HS-Glycoprotein [S]

YH Lin, J Zhu, S Meijer, V Franc, AJR Heck - Molecular & Cellular …, 2019 - ASBMB
Fetuin, also known as α-2-HS-glycoprotein (gene name: AHSG), is one of the more
abundant glycoproteins secreted into the bloodstream. There are two frequently occurring …

Similar albeit not the same: in-depth analysis of proteoforms of human serum, bovine serum, and recombinant human fetuin

YH Lin, V Franc, AJR Heck - Journal of proteome research, 2018 - ACS Publications
Fetuin, also known as alpha-2-Heremans Schmid glycoprotein (AHSG), belongs to some of
the most abundant glycoproteins secreted into the bloodstream. In blood, fetuins exhibit …

Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium

MK Jensen, RA Jensen, KJ Mukamal… - Human molecular …, 2017 - academic.oup.com
Plasma fetuin-A is associated with type 2 diabetes, and AHSG, the gene encoding fetuin-A,
has been identified as a susceptibility locus for diabetes and metabolic syndrome. Thus far …

Haplotype analysis of the human α2‐HS glycoprotein (fetuin) gene

M Osawa, I Yuasa, T Kitano, J Henke… - Annals of human …, 2001 - Wiley Online Library
Alpha2‐HS glycoprotein (AHSG), which is equivalent to fetuin in other species, is a protein
found in human plasma. AHSG is polymorphic with two common alleles and many variants …

Posttranslational Processing of Human α2‐HS Glycoprotein (Human Fetuin) Evidence for the Production of a Phosphorylated Single‐Chain Form by Hepatoma Cells

W Jahnen‐Dechent, A Trindl… - European Journal of …, 1994 - Wiley Online Library
α2‐HS glycoprotein (α2‐HS) is a major protein occuring in human blood and calciferous
tissues. Due to extensive sequence identity, α2‐HS has been grouped with the fetuins, a …

Poor agreement between commercial ELISAs for plasma fetuin-A: An effect of protein glycosylation?

ER Smith, ML Ford, LA Tomlinson, BF Rocks… - Clinica Chimica …, 2010 - Elsevier
BACKGROUND: Fetuin-A is a circulating inhibitor of ectopic calcification. Low plasma levels
have been associated in some studies with increased vascular calcification, aortic stiffness …

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

E Fisher, N Stefan, K Saar, D Drogan… - Circulation …, 2009 - Am Heart Assoc
Background—Elevated circulating levels of fetuin-A in blood have been associated with
increased risk of cardiovascular disease. The goal of our study was to prospectively …

[HTML][HTML] Low fetuin-A levels are associated with cardiovascular death: impact of variations in the gene encoding fetuin

P Stenvinkel, K Wang, AR Qureshi, J Axelsson… - Kidney international, 2005 - Elsevier
Low fetuin-A levels are associated with cardiovascular death: Impact of variations in the
gene encoding fetuin. Background Vascular calcification is common among end-stage renal …

Fetuin-A: a multifunctional protein

K Mori, M Emoto, M Inaba - Recent patents on endocrine …, 2011 - ingentaconnect.com
Sixty-six years have elapsed since the discovery of fetuin in 1944, but its importance in
mammalian physiology has only recently been appreciated. Fetuin, first isolated from fetal …

Genetically elevated fetuin-A levels, fasting glucose levels, and risk of type 2 diabetes: the cardiovascular health study

MK Jensen, TM Bartz, L Djoussé, JR Kizer… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE Fetuin-A levels are associated with higher risk of type 2 diabetes, but it is
unknown if the association is causal. We investigated common (> 5%) genetic variants in the …