Control of self-renewal and differentiation of human ES cells (hESCs) remains a challenge.
This is largely due to the use of culture systems that involve poorly defined animal products …

The propagation of human embryonic stem cells (hESCs) in three-dimensional (3D)
scaffolds facilitates the cell expansion process and supplies pluripotent cells of high quality …

A major limitation in developing applications for the use of human embryonic stem cells
(HESCs) is our lack of knowledge of their responses to specific cues that control self …

Human embryonic stem cells (hESCs) have the potential to differentiate into all cell types in
the body and hold great promise for regenerative medicine; however, large‐scale expansion …

We report a fully defined synthetic polymer coating, poly [2-(methacryloyloxy) ethyl dimethyl-
(3-sulfopropyl) ammonium hydroxide](PMEDSAH), which sustains long-term human …

Chemically defined medium (CDM) conditions for controlling human embryonic stem cell
(hESC) fate will not only facilitate the practical application of hESCs in research and therapy …

We propose a new methodology to enhance the vascular differentiation of human embryonic
stem cells (hESCs) by encapsulation in a bioactive hydrogel. hESCs were encapsulated in a …

ES (embryonic stem) cell differentiation is dependent on the presence of HS (heparan
sulfate). We have demonstrated that, during differentiation, the evolution of specific cell …

Differentiation of embryonic stem (ES) cells generally occurs after formation of three-
dimensional cell aggregates, known as embryoid bodies (EBs). We have previously …

We have developed a synthetic polymer interface for the long-term self-renewal of human
embryonic stem cells (hESCs) in defined media. We successfully cultured hESCs on …