Restricted expression of Mov13 mutant α1 (I) collagen gene in osteoblasts and its consequences for bone development

K Kratochwil, N Ghaffari‐Tabrizi… - Developmental …, 1993 - Wiley Online Library
Cell type-specific differences in the transcriptional control of the mouse gene coding for the
a1 chain of collagen type I (Collal) have been revealed previously with the help of the Movl3 …

Transcription of a mutant collagen I gene is a cell type and stage-specific marker for odontoblast and osteoblast differentiation

M Schwarz, K Harbers, K Kratochwil - Development, 1990 - journals.biologists.com
The Movl3 allele of the mouse al (I) collagen gene carries a retroviral insert in its first intron
and had been reported to be transcriptionally silent. We have recently shown, however, that …

Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner

K Kratochwil, K von der Mark, EJ Kollar, R Jaenisch… - Cell, 1989 - cell.com
In the Mov73 mouse mutant, transcription of the al (l) collagen gene is blocked by a retroviral
insert in the first intron. We now report that teeth derived from homozygous embryos produce …

Collagen synthesis by cell lines derived from Mov-13 mouse embryos which have a lethal mutation in the collagen α 1 (I) gene

M Dziadek, R Timpl, R Jaenisch - Biochemical Journal, 1987 - portlandpress.com
Mouse embryos homozygous for the Mov-13 mutation produce no collagen I, owing to
transcriptional blockage of the collagen alpha 1 (I) gene by a retroviral insert. Fibroblast-like …

Structure of the mouse type XV collagen gene, Col15a1, comparison with the human COL15A1 gene and functional analysis of the promoters of both genes

L Eklund, A Muona, J Liétard, T Pihlajaniemi - Matrix Biology, 2000 - Elsevier
Isolation and characterization of the mouse gene for the α1 chain of type XV collagen
(Col15a1) revealed it to be approximately 110 kb in length and contain 40 exons. Analysis of …

Differential utilization of regulatory domains within the alpha 1 (I) collagen promoter in osseous and fibroblastic cells.

D Pavlin, AC Lichtler, A Bedalov, BE Kream… - The Journal of cell …, 1992 - rupress.org
Type I collagen is expressed in a variety of connective tissue cells and its transcriptional
regulation is highly complex because of the influence of numerous developmental …

Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure

M Breindl, K Harbers, R Jaenisch - Cell, 1984 - cell.com
The chromatin structure of the collagen al (l) gene, which has been mutated by retrovirus
insertion in Movl3 mice, was compared with that of the wildtype allele. Limited digestions …

Use of the collagen I-deficient Mov13 mouse mutant to analyse epithelial-mesenchymal tissue interaction

K Kratochwil - Cell Differentiation and Development, 1988 - Elsevier
The collagen I-deficient mouse mutant (Mov13—an embryonic recessive lethal) was used to
investigate the function of this major constituent of the extracellular matrix (ECM) in organ …

Regulation of COL1A1 expression in type I collagen producing tissues: identification of a 49 base pair region which is required for transgene expression in bone of …

A Bedalov, R Salvatori, M Dodig… - Journal of Bone and …, 1995 - Wiley Online Library
Previous deletion studies using a series of COL1A1‐CAT fusion genes have indicated that
the 625 bp region of the COL1A1 upstream promoter between‐2295 and‐1670 bp is …

Sp7/Osterix is involved in the up-regulation of the mouse pro-α1 (V) collagen gene (Col5a1) in osteoblastic cells

YF Wu, N Matsuo, H Sumiyoshi, H Yoshioka - Matrix Biology, 2010 - Elsevier
Sp7/Osterix, a transcription factor whose expression is restricted in osteoblasts, belongs to
the Sp family of transcription factor that bind to G/C-rich sequences. Previous studies have …