Cytokine networks in Pemphigus vulgaris: An integrated viewpoint
CN Giordano, AA Sinha - Autoimmunity, 2012 - Taylor & Francis
Pemphigus vulgaris (PV) is an autoimmune bullous skin disease where tolerance to the
desmosomal protein desmoglein 3 (Dsg3), and perhaps additional epidermal targets, is lost …
desmosomal protein desmoglein 3 (Dsg3), and perhaps additional epidermal targets, is lost …
[HTML][HTML] Th1/Th17-related cytokines and chemokines and their implications in the pathogenesis of pemphigus vulgaris
Pemphigus vulgaris (PV) is an autoimmune disease characterized by the presence of IgG
autoantibodies against desmoglein-3. Despite the variety of findings, the chemokine and …
autoantibodies against desmoglein-3. Despite the variety of findings, the chemokine and …
[HTML][HTML] The cytokine milieu of bullous pemphigoid: Current and novel therapeutic targets
R Maglie, F Solimani, D Didona, C Pipitò… - Frontiers in …, 2023 - frontiersin.org
Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized
by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also …
by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also …
[HTML][HTML] Autoimmune pemphigus: latest advances and emerging therapies
Pemphigus represents a group of rare and severe autoimmune intra-epidermal blistering
diseases affecting the skin and mucous membranes. These painful and debilitating diseases …
diseases affecting the skin and mucous membranes. These painful and debilitating diseases …
Deregulated phenotype of autoreactive Th17 and Treg clone cells in pemphigus vulgaris after in-vitro treatment with desmoglein antigen (Dsg-3)
The loss of balance between regulatory T (Treg) and T helper 17 (Th17) causes loss of
tolerance against desmoglein (Dsg)-3 leading to pemphigus vulgaris (PV), an autoimmune …
tolerance against desmoglein (Dsg)-3 leading to pemphigus vulgaris (PV), an autoimmune …
Direct characterization of human T cells in pemphigus vulgaris reveals elevated autoantigen‐specific Th2 activity in association with active disease
C Rizzo, M Fotino, Y Zhang, S Chow… - Clinical and …, 2005 - academic.oup.com
Pemphigus vulgaris (PV) is a blistering skin disorder mediated by autoantibodies targeting
the epidermal adhesion molecule desmoglein 3 (Dsg3). As Th2‐associated cytokines are …
the epidermal adhesion molecule desmoglein 3 (Dsg3). As Th2‐associated cytokines are …
The imbalance of Th17 and regulatory T cells in pemphigus patients
RC Xu, HQ Zhu, WP Li, XQ Zhao, HJ Yuan… - European Journal of …, 2013 - jle.com
Pemphigus is a complex dermatologic autoimmune bullous disease whose pathogenic
mechanism is not fully understood. Anti-desmoglein-1 (Dsg1) and anti-Dsg3 autoantibodies …
mechanism is not fully understood. Anti-desmoglein-1 (Dsg1) and anti-Dsg3 autoantibodies …
Immunophenotyping in pemphigus reveals a TH17/TFH17 cell–dominated immune response promoting desmoglein1/3-specific autoantibody production
J Holstein, F Solimani, C Baum, K Meier… - Journal of Allergy and …, 2021 - Elsevier
Background TH 2 cells were thought to be a pivotal factor for initiation of the autoimmune
blistering disease pemphigus. However, the role of other T-cell subsets in pemphigus …
blistering disease pemphigus. However, the role of other T-cell subsets in pemphigus …
Pathogenic and protective roles of cytokines in pemphigus: a systematic review
Pemphigus is a rare and life-threatening group of blistering autoimmune diseases that
affects the skin and mucous membranes. There are two major subtypes of pemphigus …
affects the skin and mucous membranes. There are two major subtypes of pemphigus …
Immune cells in pemphigus vulgaris and bullous Pemphigoid: From pathogenic roles to targeting therapies
Q Yuan, W Yang, X Zhang - International Immunopharmacology, 2023 - Elsevier
Pemphigus vulgaris (PV) and bullous pemphigoid (BP) are two major subtypes of
autoimmune bullous diseases (AIBD), characterized by blisters and erosions of skin and/or …
autoimmune bullous diseases (AIBD), characterized by blisters and erosions of skin and/or …
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