Genome-wide association study of Alzheimer's disease with psychotic symptoms
Psychotic symptoms occur in∼ 40% of subjects with Alzheimer's disease (AD) and are
associated with more rapid cognitive decline and increased functional deficits. They show …
associated with more rapid cognitive decline and increased functional deficits. They show …
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
MAA DeMichele-Sweet, L Klei, B Creese… - Molecular …, 2021 - nature.com
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent
in Alzheimer disease (AD with psychosis, AD+ P). AD+ P affects~ 50% of individuals with …
in Alzheimer disease (AD with psychosis, AD+ P). AD+ P affects~ 50% of individuals with …
Genetic risk for schizophrenia and psychosis in Alzheimer disease
MAA DeMichele-Sweet, EA Weamer, L Klei… - Molecular …, 2018 - nature.com
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent
in Alzheimer disease (AD), affecting~ 40 to 60% of individuals with AD (AD with psychosis …
in Alzheimer disease (AD), affecting~ 40 to 60% of individuals with AD (AD with psychosis …
Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data
Major depressive disorder (MDD) and Alzheimer's disease (AD) are both common in older
age and frequently co-occur. Numerous phenotypic studies based on clinical diagnoses …
age and frequently co-occur. Numerous phenotypic studies based on clinical diagnoses …
Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis
P Hollingworth, ML Hamshere… - American Journal of …, 2007 - Wiley Online Library
Psychotic symptoms are common in Alzheimer's disease (AD) and are associated with
increased cognitive impairment and earlier institutionalization. One study has suggested that …
increased cognitive impairment and earlier institutionalization. One study has suggested that …
Genome-wide association study of Alzheimer's disease
In addition to apolipoprotein E (APOE), recent large genome-wide association studies
(GWASs) have identified nine other genes/loci (CR1, BIN1, CLU, PICALM, MS4A4/MS4A6E …
(GWASs) have identified nine other genes/loci (CR1, BIN1, CLU, PICALM, MS4A4/MS4A6E …
Genetics of psychosis of Alzheimer disease
C Shah, MAA DeMichele‐Sweet… - American Journal of …, 2017 - Wiley Online Library
Psychotic symptoms, comprised of delusions and hallucinations, occur in about half of
individuals with Alzheimer disease (AD with psychosis, AD+ P). These individuals have …
individuals with Alzheimer disease (AD with psychosis, AD+ P). These individuals have …
A novel Alzheimer disease locus located near the gene encoding tau protein
G Jun, CA Ibrahim-Verbaas, M Vronskaya… - Molecular …, 2016 - nature.com
APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask
effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the …
effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the …
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
Psychosis (delusions or hallucinations) in Alzheimer's disease (AD+ P) occurs in up to 50%
of individuals and is associated with significantly worse clinical outcomes. Atypical …
of individuals and is associated with significantly worse clinical outcomes. Atypical …
Psychotic symptoms in Alzheimer disease: evidence for a distinct phenotype
Though efforts to identify the genetic etiology of Alzheimer disease (AD) have made
substantial progress, to date only some of the genes contributing to AD risk have been …
substantial progress, to date only some of the genes contributing to AD risk have been …