Herein we present, an exhaustive docking analysis considering the case of autotaxin (ATX).
HA155, a small molecule inhibitor of ATX, is co-crystallized. In order to further extract …

Autotaxin (ATX) is a secreted glycoprotein, widely present in biological fluids, largely
responsible for extracellular lysophosphatidic acid (LPA) production. LPA is a bioactive …

Robust experimental evidence has highlighted the role of Autotaxin (ATX)/Lysophosphatidic
acid (LPA) axis not only in the pathogenesis of chronic inflammatory conditions and …

Autotaxin is a secreted lysophospholipase D which is a member of the ectonucleotide
pyrophosphatase/phosphodiesterase family converting extracellular …

The autotaxin (ATX) enzyme exhibits lysophospholipase D activity responsible for the
conversion of lysophosphatidyl choline to lysophosphatidic acid (LPA). ATX and LPA have …

Autotaxin (ATX) is a potential target for the treatment of various cancers. A new series of ATX
inhibitors was rationally designed and synthesized based on our previous study. Biological …

The autotaxin-lysophophatidic acid (ATX-LPA) signaling pathway is involved in several
human diseases such as cancer, autoimmune diseases, inflammatory diseases …

Autotaxin (ATX) is an enzyme primarily known for the production of lysophosphatidic acid.
Being involved in the development of major human diseases, such as cancer and …

Several years after its isolation from melanoma cells, an increasing body of experimental
evidence has established the involvement of Autotaxin (ATX) in the pathogenesis of several …

Autotaxin (ATX), also known as ectonucleotide pyrophosphatase/phosphodiesterase 2
(ENPP2), was originally identified as a tumor cell autocrine motility factor and was found to …