Objective: To investigate the antifibrotic role of rosmarinic acid (RA), a natural polyphenolic
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods: The …

Objective To investigate the antifibrotic role of rosmarinic acid (RA), a natural polyphenolic
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods The …

This study was carried out to investigate whether rosmarinic acid (RA) has antifibrotic effect
on experimental liver fibrosis in vitro and in vivo and its possible mechanism. Culture of …

Despite rutin, extracted from black mulberry, has several pharmacological activities, its exact
effect against hepatic fibrosis remains incompletely identified. Accordingly, this study …

Objective: To investigate the antifibrotic effects of Chrysanthemum indicum ethanol extract
(CIEE) against activated hepatic stellate cells (HSC) and thioacetamide (TAA)-induced …

Objective: To evaluate the effect of hydroxysafflor yellow A (HSYA) on thioacetamide-
induced liver fibrosis. Methods: Thioacetamide was administered to rats intraperitoneally in …

Hepatic fibrosis is a wound-healing process caused by prolonged liver damage and often
occurs due to hepatic stellate cell activation in response to reactive oxygen species (ROS) …

Purpose: To evaluate the anti-fibrotic effects of ethanol extract of Rhus javanica
Linn.(Anacardiaceae)(RJE) in activated hepatic stellate cells (HSCs) as well as explore the …

Recently, oxidative stress is involved in hepatofibrogenesis. Matrix metalloproteinase-2
(MMP-2) is required for activation of hepatic stellate cells (HSCs) in response to reactive …

Background and Objectives: Non-Alcoholic Steatohepatitis (NASH) is a serious and
increasing liver disease, which develops into cirrhosis, fibrosis, and hepatocellular …