Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid

CH Wu, HN Murthy, EJ Hahn, KY Paek - Biotechnology letters, 2007 - Springer
Adventitious roots of Echinacea purpurea were cultured in airlift bioreactors (20 l, 500 l
balloon-type, bubble bioreactors and 1,000 l drum-type bubble bioreactor) using Murashige …

Scale-up of adventitious root cultures of Echinacea angustifolia in a pilot-scale bioreactor for the production of biomass and caffeic acid derivatives

HY Cui, M Abdullahil Baque, EJ Lee… - Plant biotechnology reports, 2013 - Springer
In an attempt to scale-up of adventitious root cultures of Echinacea angustifolia for the
production of biomass and caffeic acid derivatives, ie echinacoside, chlorogenic acid …

Cichoric acid production from hairy root cultures of Echinacea purpurea grown in a modified airlift bioreactor

BH Abbasi, R Liu, PK Saxena… - Journal of Chemical …, 2009 - Wiley Online Library
BACKGROUND: Hairy root cultures of Echinacea offer great potential for the production of
valuable cichoric acid, but scale‐up of the culture in the bioreactor represents a big …

Application of an airlift bioreactor system for the production of adventitious root biomass and caffeic acid derivatives of Echinacea purpurea

JA Jeong, CH Wu, HN Murthy, EJ Hahn… - Biotechnology and …, 2009 - Springer
In this study, we evaluated the feasibility of using mass cultivation of the adventitious roots of
Echinacea purpurea in balloon type bubble (air-lift) bioreactors to produce caffeic acid …

Enhanced production of caftaric acid, chlorogenic acid and cichoric acid in suspension cultures of Echinacea purpurea by the manipulation of incubation temperature …

CH Wu, HN Murthy, EJ Hahn, KY Paek - Biochemical Engineering Journal, 2007 - Elsevier
The effects of temperature and light irradiation (photoperiod) on growth and production of
caffeic acid derivatives (caftaric acid, chlorogenic acid and cichoric acid) were studied in …

Biotechnological production of caffeic acid derivatives from cell and organ cultures of Echinacea species

HN Murthy, YS Kim, SY Park, KY Paek - Applied microbiology and …, 2014 - Springer
Caffeic acid derivatives (CADs) are a group of bioactive compounds which are produced in
Echinacea species especially Echinacea purpurea, Echinacea angustifolia, and Echinacea …

Improved production of caffeic acid derivatives in suspension cultures ofEchinacea purpurea by medium replenishment strategy

CH Wu, HN Murthy, EJ Hahn, KY Paek - Archives of Pharmacal Research, 2007 - Springer
The aim of this study was to produce caffeic acid derivatives from adventitious root cultures
of Echinacea purpurea, which are of high pharmaceutical value. The effects of both media …

Optimizing co-culture conditions of adventitious roots of Echinacea pallida and Echinacea purpurea in air-lift bioreactor systems

CH Wu, J Tang, ZX Jin, M Wang, ZQ Liu… - Biochemical …, 2018 - Elsevier
Co-culture is a new strategy to enhance metabolite biosynthesis of plants. In the present
study, effects of Murashige and Skoog (MS) medium strengths and sucrose concentrations …

Caffeic Acid Derivatives Production by Hairy Root Cultures of Echinacea purpurea

CZ Liu, BH Abbasi, M Gao, SJ Murch… - Journal of agricultural …, 2006 - ACS Publications
Inoculation of leaf explants of Echinacea purpurea (Moench) with Agrobacterium rhizogenes
induced hairy roots with the capacity to produce biologically active caffeic acid derivatives …

[HTML][HTML] Optimization of callus cultures at Echinacea purpurea L. for the amount of caffeic acid derivatives

MT Erkoyuncu, M Yorgancilar - Electronic Journal of Biotechnology, 2021 - Elsevier
Background In order to produce an effective callus in Echinacea purpurea L.; determination
of the explant type and growth regulators that best respond to callus induction and the …