[HTML][HTML] Anti-apoptotic effect of G-protein-coupled receptor 40 activation on tumor necrosis factor-α-induced injury of rat proximal tubular cells
CS Kim, SY Joo, IJ Kim, HI Choi, EH Bae… - International Journal of …, 2019 - mdpi.com
G-protein-coupled receptor 40 (GPR40) has an anti-apoptotic effect in pancreatic β-cells.
However, its role in renal tubular cell apoptosis remains unclear. To explore the role of …
However, its role in renal tubular cell apoptosis remains unclear. To explore the role of …
[HTML][HTML] Activation of G-protein-coupled receptor 40 attenuates the cisplatin-induced apoptosis of human renal proximal tubule epithelial cells
SK Ma, SY Joo, HI Choi, EH Bae… - International …, 2014 - spandidos-publications.com
Abstract G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of
fatty acids, insulin secretion and inflammation. However, the pathophysiological roles of …
fatty acids, insulin secretion and inflammation. However, the pathophysiological roles of …
Overexpression of RGPR-p117 suppresses apoptotic cell death and its related gene expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells
M Yamaguchi, S Tomono… - … journal of molecular …, 2007 - spandidos-publications.com
The novel protein RGPR-p117 was discovered as a regucalcin gene promoter region-
related protein that binds to the TTGGC motif using a yeast one-hybrid system. The role of …
related protein that binds to the TTGGC motif using a yeast one-hybrid system. The role of …
[HTML][HTML] G protein-coupled receptor 87 (GPR87) promotes cell proliferation in human bladder cancer cells
X Zhang, D Liu, Y Hayashida, H Okazoe… - International journal of …, 2015 - mdpi.com
G protein-coupled receptor 87 (GPR87) is a newly deorphanized member of the cell surface
molecule G protein-coupled receptor family. GPR signaling was shown to play a role in …
molecule G protein-coupled receptor family. GPR signaling was shown to play a role in …
G protein-coupled receptor 39 plays an anti-inflammatory role by enhancing IL-10 production from macrophages under inflammatory conditions
S Muneoka, M Goto, K Kadoshima-Yamaoka… - European journal of …, 2018 - Elsevier
The possible role of G protein-coupled receptor 39 (GPR39) in inflammation was examined
in macrophages. Gpr39 expression increased in thioglycollate-induced peritoneal …
in macrophages. Gpr39 expression increased in thioglycollate-induced peritoneal …
GPR4 knockout improves renal ischemia–reperfusion injury and inhibits apoptosis via suppressing the expression of CHOP
B Dong, X Zhang, Y Fan, S Cao, X Zhang - Biochemical Journal, 2017 - portlandpress.com
The aim of the present study was to investigate the effects and molecular mechanisms of
GPR4 (G-protein-coupled receptor 4) in cell apoptosis and renal ischemia–reperfusion (IR) …
GPR4 (G-protein-coupled receptor 4) in cell apoptosis and renal ischemia–reperfusion (IR) …
Expression of G protein coupled receptor 87 (GPR87) in end stage renal disease and associated tumours
A Nagy, B Hegedus, Z Kuronya, K Biro, T Beothe - 2023 - researchsquare.com
End stage renal disease (ESRD) and acquired cystic renal disease (ACRD) are
characterized by structural remodelling through chronic inflammation and by frequent …
characterized by structural remodelling through chronic inflammation and by frequent …
[HTML][HTML] G‑protein‑coupled receptor 120 regulates the development and progression of human esophageal cancer
Z Cui, D Li, J Liu, Y Zhang, H Xu, H Yin… - Oncology …, 2018 - spandidos-publications.com
The aim of the present study was to investigate the role of G‑protein coupled receptor 120
(GPR120) in esophageal cancer and explore the related mechanisms. The expression of …
(GPR120) in esophageal cancer and explore the related mechanisms. The expression of …
The overexpressed transcription factor RGPR-p117 suppresses the proliferation of normal rat kidney proximal tubular epithelial NRK-52E cells: Involvement of diverse …
Aims RGPR-p117 was originally discovered as a novel transcription factor, which
specifically binds to a nuclear factor I (NFI) consensus motif TTGGC (N) 6 CC in the promoter …
specifically binds to a nuclear factor I (NFI) consensus motif TTGGC (N) 6 CC in the promoter …
[HTML][HTML] CID16020046, a GPR55 antagonist, attenuates sepsis‑induced acute kidney injury
R Chen, H Xu, Z Guo, P Zhang… - Molecular Medicine …, 2022 - spandidos-publications.com
Acute kidney injury (AKI) is the most common and serious complication of sepsis, and it is
also the main cause of mortality in patients with sepsis. The G protein‑coupled receptor 55 …
also the main cause of mortality in patients with sepsis. The G protein‑coupled receptor 55 …