NUT midline carcinoma (NMC) belongs to a class of highly lethal and poorly differentiated
epithelial cancers arising mainly in human midline organs. NMC is caused by the …

NUT midline carcinoma (NMC) is a rare but highly aggressive cancer typically caused by the
translocation t (15; 19), which results in the formation of the BRD4-NUT fusion oncoprotein …

Nuclear protein in testis (NUT)-midline carcinoma (NMC) is a rare, aggressive disease
typically presenting with a single t (15; 19) translocation that results in the generation of a …

BRD4 is implicated in the pathogenesis of a number of different cancers. It is also the target
of translocation t (15; 19) that accounts for the highly aggressive NUT midline carcinoma …

NUT carcinoma (NC) is an extremely aggressive squamous cancer with no effective therapy.
NC is driven, most commonly, by the BRD4-NUT fusion oncoprotein. BRD4-NUT combines …

NUT midline carcinoma (NMC) is an aggressive type of squamous cell carcinoma that is
defined by the presence of BRD-NUT fusion oncogenes, which encode chimeric proteins …

To investigate the mechanism that drives dramatic mistargeting of active chromatin in NUT
midline carcinoma (NMC), we have identified protein interactions unique to the BRD4–NUT …

Defects in chromatin proteins frequently manifest in diseases. A striking case of a chromatin-
centric disease is NUT-midline carcinoma (NMC), which is characterized by expression of …

An unusual group of carcinomas, here termed nuclear protein in testis (NUT) midline
carcinomas (NMC), are characterized by translocations that involve NUT, a novel gene on …

NUT midline carcinoma (NMC), a subtype of squamous cell cancer, is one of the most
aggressive human solid malignancies known. NMC is driven by the creation of a …